颌面部骨修复材料的应用与研究进展  

Clinical applications and progress of bone repair materials in maxillofacial area

作　　者：吴茜 王永前 Wu Qian;Wang Yongqian(Center for Cleft Lip and Palate Treatment,Plastic Surgery Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100144,China)

机构地区：[1]中国医学科学院北京协和医学院整形外科医院唇腭裂中心,北京100144

出　　处：《中华整形外科杂志》2022年第6期713-719,共7页Chinese Journal of Plastic Surgery

基　　金：首都医学发展基金项目(2020-2-4041);北京协和医学院教学改革项目(10023201504024、10023201900401)。

摘　　要：颌面部骨缺损发病率居高不下,其骨修复重建正在追求个性化、精准化、微创化和高效率,颌面部骨修复材料一直是临床医学和生物组织工程学中的研究热点。该综述对颌面部骨缺损的特点及病因、颌面部骨缺损的修复方法作了介绍,对颌面部骨修复材料的特点及临床应用进行了全面的总结对比。纵观全局,目前颌面部骨修复材料仍面临许多瓶颈问题,其研究前景十分广阔。The incidence of maxillofacial bone defect is high.We are pursuing individualized,precise,minimally invasive and highly efficient maxillofacial bone reconstruction.Maxillofacial bone repair materials have always been the focus of clinical medicine and biological tissue engineering.In this review,the characteristics and causes of maxillofacial bone defects,and the repairing methods of maxillofacial bone defects were introduced.The characteristics and clinical application of maxillofacial bone repair materials were comprehensively summarized and compared.Overall,there are still many bottlenecks,and the research prospects of maxillofacial bone repair materials are very broad.

关 键 词：颌面外科 骨移植物 骨替代材料 组织工程 引导骨再生 

分 类 号：R782.2[医药卫生—口腔医学]