围绝经期女性维持性血液透析患者的抑郁症发病现状及相关因素分析  

Analysis on the current situation and related factors of depression in perimenopausal women undergoing maintenance hemodialysis

作　　者：陈海燕[1] 郑淑瑛[1] 黄莹莹 徐安琪 谢莉[1] 黄文[1] CHEN Hai-Yan;ZHENG Shu-Ying;HUANG Ying-Ying(Department of Nephrology,the Second Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang 325000,China)

机构地区：[1]温州医科大学附属第二医院肾内科,浙江温州325000

出　　处：《中国妇幼保健》2022年第13期2331-2334,共4页Maternal and Child Health Care of China

摘　　要：目的 调查分析围绝经期女性维持性血液透析患者的抑郁症发病现状并探讨其影响因素,为防治工作提供可靠的参考依据。方法 选取2017年1月—2019年12月在温州医科大学附属第二医院肾内科行维持性血液透析治疗的围绝经期女性患者120例为研究对象,调查获取患者的人口学特征、生活行为方式及临床治疗信息,采用抑郁自评量表(SDS)对患者抑郁情况进行评估,分析不同人口学特征、生活行为方式及临床治疗信息患者的抑郁症发病率,并通过多因素logistic回归分析判定其影响因素。结果 120例围绝经期女性维持性血液透析患者的SDS均分为(51.9±4.2)分,抑郁症发病26例、发病率为21.7%,其中轻度抑郁12例、中度抑郁10例、重度抑郁4例。单因素分析显示51~60岁、居住地乡镇、丧偶/离异、未积极体育锻炼、睡眠质量差、已绝经、有基础疾病、人工血管动静脉内瘘、透析次数≥3次/周及透析龄>12个月的围绝经期女性维持性血液透析患者抑郁症发病率更高(P<0.05)。多因素logistic回归分析显示年龄、睡眠、基础疾病、血管通路方式、透析次数及透析龄是围绝经期女性维持性血液透析患者抑郁症发病的影响因素。结论 围绝经期女性维持性血液透析患者的抑郁症发病率较高,可根据其发病的影响因素采取针对性干预措施,有效改善患者的心理状态,帮助其积极面对疾病并配合维持性血液透析治疗,获得良好预后。Objective To survey and analyze the current situation of depression in perimenopausal women undergoing maintenance hemodialysis, explore the influencing factors, and provide a reliable reference basis for prevention and treatment work. Methods From January 2017 to December 2019, 120 perimenopausal women undergoing maintenance hemodialysis in Department of Nephrology, the Second Affiliated Hospital of Wenzhou Medical University were selected as study object, demographic characteristics, living and behavioral characteristics, and clinical treatment information were surveyed, Self-Rating Depression Scale(SDS) was used to evaluate depression, the incidence rates of depression in perimenopausal women of different demographic characteristics, living and behavioral characteristics, and clinical treatment information were analyzed, multivariate logistic regression analysis was used to analyze the influencing factors. Results The average score of SDS scale was(51.9±4.2), the incidence rate of depression was 21.7%(26 cases), including 12 cases with mild depression, 10 cases with moderate depression, and 4 cases with severe depression. Univariate analysis showed that the perimenopausal women of 51-60 years old, living in villages and towns, widowed or divorced women, inactive physical exercise, poor sleep quality, postmenopause, having basic diseases, arteriovenous fistulations with artificial vessels, times of hemodialysis≥3 times per week, and hemodialysis time more than 12 months had higher incidence rates of depression(P<0.05). Multivariate logistic regression analysis showed that age, sleep, basic diseases, ways of vascular access, times of hemodialysis, and hemodialysis time were influencing factors of depression in perimenopausal women undergoing maintenance hemodialysis. Conclusion The incidence rate of depression in perimenopausal women undergoing maintenance hemodialysis is high, corresponding intervention measures should be taken according to the influencing factors of depression to effectively improve psychol

关 键 词：围绝经期 女性 维持性血液透析 抑郁症 影响因素 

分 类 号：R749.42[医药卫生—神经病学与精神病学]