聚甘油脂肪酸酯的结构鉴定  

Structural Identification of Polyglycerol Fatty Acid Esters

作　　者：林晓珊 罗辉泰 黄芳 梁梓洋 周熙 梁梓豪 朱志鑫 邓欣 吴惠勤 LIN Xiao-shan;LUO Hui-tai;HUANG Fang;LIANG Zi-yang;ZHOU Xi;LIANG Zi-hao;ZHU Zhi-xin;DENG Xin;WU Hui-qin(Guangdong Provincial Engineering Research Center for Quality and Safety of Traditional Chinese Medicine,Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology,Institute of Analysis,Guangdong Academy of Sciences(China National Analytical Center,Guangzhou),Guangzhou 510070,China)

机构地区：[1]广东省科学院测试分析研究所(中国广州分析测试中心)广东省化学测量与应急检测技术重点实验室,广东省中药质量安全工程技术研究中心,广东广州510070

出　　处：《分析测试学报》2022年第8期1185-1192,共8页Journal of Instrumental Analysis

摘　　要：该文采用傅里叶变换离子回旋共振质谱(FT-ICR-MS)、核磁共振氢谱(1H NMR)以及气相色谱-质谱(GC-MS)技术,对聚甘油脂肪酸酯的结构进行鉴定。样品溶解后进行FT-ICR-MS测定,根据精确分子离子数据,推测出聚甘油脂肪酸酯的基本结构以及甘油的聚合度,并采用1H NMR进行了验证。将聚甘油脂肪酸酯水解后,对脂肪酸部分进行甲酯化,经正庚烷萃取,由GC-MS测定,分析脂肪酸的组成。综合以上结果最终确定了聚甘油脂肪酸酯的结构。该研究为聚合物的结构鉴定提供了一种新的思路和方法。A method for the structural identification of polyglycerol fatty acid esters was developed by Fourier transform ion cyclotron resonance mass spectrometry(FT-ICR-MS),nuclear magnetic res⁃onance hydrogen(1H NMR)spectrum and gas chromatography-mass spectrometry(GC-MS).Af⁃ter the sample was dissolved,it was determined by FT-ICR-MS.According to the accurate mo⁃lecular ion data,the basic structure of polyglycerol fatty acid ester and the polymerization degree of glycerol were inferred.The basic structure of polyglycerol fatty acid ester and the polymerization de⁃gree of glycerol were further verified by 1H NMR.After hydrolysis,the fatty acid part was methylat⁃ed,then extracted with n-heptane,and finally determined by GC-MS.Based on the above results,the structure of polyglycerol fatty acid ester was determined.This study provides a new idea and method for the structural identification of polymers.

关 键 词：傅里叶变换离子回旋共振质谱(FT-ICR-MS) 核磁共振(NMR) 气相色谱-质谱(GC-MS) 聚甘油脂肪酸酯 结构鉴定 

分 类 号：O657.7[理学—分析化学] O632[理学—化学]