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作 者:董立萍 车福健 张丽 DONG Liping;CHE Fujian;ZHANG Li(Kaifeng People's Hospital,Kaifeng,475000)
机构地区:[1]河南省开封市人民医院,475000 [2]开封大学医学部,475000
出 处:《实用癌症杂志》2022年第8期1327-1330,共4页The Practical Journal of Cancer
摘 要:目的探究彩色多普勒超声检测血流动力学对原发性肝癌合并门静脉高压及术后复发评估的临床价值。方法选择原发性肝癌合并门静脉高压患者106例作为观察组,选择同期体检健康人100例作为对照组,均采用彩色多普勒超声进行检测。比较2组门静脉、脾静脉血流动力学指标。观察组患者均行手术,术后1年根据是否复发分为复发组及未复发组,比较2组的肝动脉、门静脉血流动力学指标。结果观察组的门静脉内径、门静脉血流量、脾静脉内径及脾静脉血流量均高于对照组(P<0.05),观察组的门静脉血流速度、脾静脉血流速度速度均低于对照组(P<0.05)。不同门静脉主干内径、脾静脉内径患者的食管胃底静脉曲张程度比较,差异有统计学意义(P<0.05),且随门静脉主干内径及脾静脉内径增加,患者食管胃底静脉曲张程度加重。复发组的肝动脉内径、门静脉内径均较未复发组增粗;复发组的肝动脉血流速度、肝动脉血流量、门静脉血流速度、门静脉血流量、肝动脉血流量/门静脉流量均高于未复发组,差异有统计学意义(P<0.05)。结论采用彩色多普勒超声检测血流动力学,有助于评估原发性肝癌合并门静脉高压,为临床诊断及治疗提供参考依据,术后随访监测有助于了解患者复发情况。Objective To explore the clinical value of color Doppler ultrasound detecting hemodynamics for primary hepatic carcinoma(PHC)combined with portal hypertension and postoperative recurrence.Methods A total of 106 patients with PHC and portal hypertension were enrolled as the observation group,while 100 healthy controls during the same period were enrolled as the control group.All were detected by color Doppler ultrasound.The hemodynamics indexes of portal vein and splenic vein were compared between the 2 groups According to presence or absence of recurrence at 1 year after surgery,they were divided into recurrence group and non-recurrence group,and hemodynamics indexes of hepatic artery and portal vein between the 2 groups were compared.Results The diameter and blood flow of portal vein and splenic vein in the observation group were higher than those in the control group(P<0.05),and blood flow velocity of portal vein and splenic vein were slower than those in control group(P<0.05).The differences in severity of esophagogastric varices among patients with different portal vein and splenic vein diameters were statistically significant(P<0.05).With the increase of portal vein and splenic vein diameters,severity of esophagogastric varices was aggravated.The hepatic artery and portal vein diameters in recurrence group were longer than those in non-recurrence group,blood flow velocity and blood flow of hepatic artery and portal vein,hepatic artery blood flow/portal vein blood flow were higher than those in non-recurrence group(P<0.05).Conclusion The hemodynamics detected by color Doppler ultrasound is beneficial to evaluate PHC combined with portal hypertension,which provides reference for clinical diagnosis and treatment.Postoperative follow-up monitoring is beneficial to understand the recurrence of patients.
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