Mathematical modeling and analysis of schistosomiasis transmission dynamics  

作　　者：Umar T.Mustapha Salihu S.Musa Muhammad A.Lawan Aliyu Abba Evren Hincal Musa D.Mohammed Bashir D.Garba Rabiu B.Yunus Shehu A.Adamu Daihai He 

机构地区：[1]Department of Mathematics Near East University TRNC Mersin 10,Turkey [2]Department of Mathematics Federal University Dutse,Nigeria [3]Department of Applied Mathematics The Hong Kong Polytechnic University,Hong Kong [4]Department of Mathematics Kano University of Science and Technology Wudil,Nigeria [5]Department of Statistics Jigawa State Polytechnic,Dutse,Nigeria [6]Department of Computer Engineering Institute of Continuing Education Kano University of Science and Technology Wudil,Nigeria [7]Department of Mathematics and Statistics Kano State Polytechnic,Nigeria

出　　处：《International Journal of Modeling, Simulation, and Scientific Computing》2021年第4期58-76,共19页建模、仿真和科学计算国际期刊（英文）

摘　　要：Schistosomiasis is a parasitic disease from the family of Schistosomatidae and genus Schistosoma,which is caused by blood flukes.The disease is endemic in many countries and still a serious threat to global public health and development.In this paper,a new deterministic model is designed and analyzed qualitatively to explore the dynamics of schistosomiasis transmission in human,cattle and snail populations.Results from our mathematical analysis show that the model has a disease-free equilibrium(DFE)which is locally asymptotically stable(LAS)whenever a particular epidemiological threshold quantity,also known as basic reproduction number(R0)is less than unity.Further analysis shows that the model has a unique endemic equilibrium(EE)which is globally asymptotically stable whenever R0>1 and unstable when R0<1.Furthermore,we adopt partial rank correlation coefficient for sensitivity analysis to reveal the most important parameters for effective control and mitigation of schistosomiasis disease in a community.Finally,we obtain some numerical results by simulating the entire dynamics of the model,which show that the infections in the compartments of each population decrease with respect to time.This further indicates that avoiding contact with infected human,cattle or infested water is vital to prevent the spread of schistosomiasis disease infection.

关 键 词：Schistosomiasis disease basic reproduction number stability analysis sensitivity analysis 

分 类 号：R73[医药卫生—肿瘤]