结肠癌术后胃瘫综合征的诊疗现状和进展  

Progress in diagnosis and treatment of gastroparesis after colon cancer surgery

作　　者：潘志忠[1] 于龙 彭健宏[1] Pan Zhizhong;Yu Long;Peng Jianhong(Department of Colorectal Surgery,State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Sun Yat-sen University Cancer Center,Guangzhou 510060,China)

机构地区：[1]中山大学肿瘤防治中心结直肠科,华南肿瘤学国家重点实验室,肿瘤医学协同创新中心,广州510060

出　　处：《中华胃肠外科杂志》2022年第6期558-562,共5页Chinese Journal of Gastrointestinal Surgery

基　　金：国家自然科学基金面上项目(82072606)。

摘　　要：目前外科手术为主导的综合治疗是结肠癌获得治愈机会的重要措施。然而,外科手术在切除肿瘤的同时,也会带来术后胃瘫的风险。由于术后胃瘫的发生风险较低,早期临床症状不明显,故往往被临床忽视。然而,术后胃瘫可增加营养不良的风险,延迟术后抗肿瘤治疗,增加肿瘤复发转移的风险。因此,本文主要就结肠癌术后胃瘫的发生机制、临床危险因素、预防措施以及治疗进展展开综述。旨在增加临床医生对结肠癌术后胃瘫的足够重视,从外科角度通过优化手术策略,降低结肠癌术后胃瘫的发生风险。At present,comprehensive treatment dominated by surgical procedures is an important measure for colon cancer to obtain the chance of cure.Surgical intervention,while removing the tumor,carries the risk of postoperative gastroparesis(PG).Because of the low incidence rate and insignificant early clinical symptoms,early stage PG is often overlooked clinically.However,PG can increase the risk of malnutrition,delay postoperative antitumor treatment,and increase the risk of tumor recurrence and metastasis.This review focuses on the mechanisms,clinical risk factors,preventive measures,and advances in treatment of PG due to colon cancer.Aim to increase the clinician's adequate attention to PG in colon cancer and from a surgical point to reduce the risk of gastroparesis in colon cancer by optimizing the surgical strategy.

关 键 词：结肠肿瘤 胃瘫综合征 发病机制 危险因素 

分 类 号：R735.35[医药卫生—肿瘤]