虹膜角膜内皮综合征发病机制及治疗  

The pathogenesis and treatment of iridocorneal endothelial syndrome

作　　者：叶雯青 邓宇轩 梁远波 Ye Wenqing;Deng Yuxuan;Liang Yuanbo(The Eye Hospital,School of Ophthalmology and Optometry,Wenzhou Medical University,Glaucoma Research Institute,Wenzhou Medical University,National Clinical Research Center for Ocular Diseases,Wenzhou 325027,China)

机构地区：[1]温州医科大学附属眼视光医院温州医科大学青光眼研究所国家眼部疾病临床医学研究中心,325027

出　　处：《国际眼科纵览》2022年第3期199-206,共8页International Review of Ophthalmology

基　　金：浙江省高层次创新人才计划(2016025);国家重点研发计划(2020YFC2008200)。

摘　　要：虹膜角膜内皮综合征的发病机制以病毒感染及Campbell膜理论为主,而病毒感染基因整合假说可能为其研究提供新思路。目前其治疗以对症为主,角膜失代偿以角膜内皮移植术为主,人工角膜移植的尝试亦初步显示良好效果,继发性青光眼则以滤过性手术为主,亦有新型微创青光眼手术及引流阀睫状沟植入术的探索。The pathogenesis of iridocorneal endothelial(ICE)syndrome are dominated by the theory of viral infection and membrane theory of Campbell.And the theory combining the infectious of virus with integration of viral genes into human genome may provide new thinking.The present treatments of ICE syndrome are focus on corneal decompensation and secondary glaucoma.The endothelial keratoplasty is the main surgery for corneal endothelial decompensation and the attempt of artificial keratoplasty shows pretty good preliminary outcome.Secondary glaucoma is mainly treated by filtering glaucoma surgery while the explore of minimally invasive glaucoma surgery and glaucoma implant device in sulcus are started to treat secondary glaucoma of ICE syndrome.

关 键 词：虹膜角膜内皮综合征 青光眼 

分 类 号：R773.1[医药卫生—眼科]