粪菌移植治疗儿童孤独症谱系障碍的研究进展  

Research Progress of Fecal Microbiota Transplantation in the Treatment of Autism Spectrum Disorders in Children

作　　者：宁怀军[1] 吴怡[1] NING Huaijun;WU Yi(Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region,Nanning 530003,China;不详)

机构地区：[1]广西壮族自治区妇幼保健院(广西儿科疾病临床医学研究中心),广西南宁530003

出　　处：《中国医学创新》2022年第21期171-174,共4页Medical Innovation of China

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(Z20210264)。

摘　　要：儿童孤独症谱系障碍是临床常见的神经发育疾病,除了广泛性发育障碍症状以外,通常伴有不同程度的胃肠道症状。目前,粪菌移植已被证实在孤独症谱系障碍的治疗中具有一定的效果,被认为有助于改善孤独症症状和胃肠道功能。本文从粪菌移植的作用机制、对肠道菌群的影响及对神经系统的影响进行综述,以期为广大同仁治疗儿童孤独症谱系障碍提供客观参考。Autism spectrum disorders is a common clinical neuro developmental disease in children.In addition to the symptoms of generalized developmental disorder,it is usually accompanied by different degrees of gastrointestinal symptoms.At present,fecal microbiota transplantation has been proved to be effective in the treatment of autism spectrum disorders,and is considered to be helpful to improve autism symptoms and gastrointestinal function.This paper reviews the mechanism of fecal microbiota transplantation,its effect on intestinal flora and its effect on nervous system,in order to provide objective reference for colleagues in the treatment of childhood autism.

关 键 词：粪菌移植 孤独症谱系障碍 肠道菌群 

分 类 号：R749.94[医药卫生—神经病学与精神病学]