Atypical imaging features of the primary spinal cord glioblastoma:A case report  

作　　者：Xin-Yu Liang Yao-Ping Chen Qiao Li Ze-Wang Zhou 

机构地区：[1]Department of Radiology,The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,Guangdong Province,China [2]Department of Radiology,The Third Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510630,Guangdong Province,China [3]Department of Endocrinology,The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2022年第22期7950-7959,共10页世界临床病例杂志

基　　金：Supported by the “Excellent Doctoral Dissertation Incubation Grant of First Clinical School of Guangzhou University of Chinese Medicine”,No. YB201903

摘　　要：BACKGROUND Primary spinal cord(PSC)glioblastoma(GB)is an extremely rare but fatal primary tumor of the central nervous system and associated with a poor prognosis.While typical tumor imaging features are generally easy to recognize,glioblastoma multiforme can have a wide range of imaging findings.Atypical GB is often misdiagnosed,which usually delays the optimal time for treatment.In this article,we discuss a clinical case of pathologically confirmed PSC GB under the guise of benign tumor imaging findings,as well as the most recent literature pertaining to PSC GB.CASE SUMMARY A 70-year-old female complained of limb weakness lasting more than 20 d.Irregular masses were observed inside and outside the left foramina of the spinal canal at C7-T1 on medical imaging.Based on the imaging features,radiologists diagnosed the patient with schwannoma.Tumor resection was performed under general anesthesia.The final histopathological findings revealed a final diagnosis of PSC GB,world health organization Grade IV.The patient subsequently underwent a 4-wk course of radiotherapy(60 Gy in 20 fractions)combined with temozolomide chemotherapy.The patient was alive at the time of submission of this manuscript.CONCLUSION Atypical GB presented unusual imaging findings,which led to misdiagnosis.Therefore,a complete recognition of imaging signs may facilitate early accurate diagnosis.

关 键 词：Primary spinal cord glioblastoma Atypical imaging features Benign-looking Misdiagnosis Pathology confirmed Case report 

分 类 号：R739.42[医药卫生—肿瘤]