Peripartum depression and its predictors:A longitudinal observational hospital-based study  

作　　者：Sherifa Ahmed Hamed Mohamed Elwasify Mohamed Abdelhafez Mohamed Fawzy 

机构地区：[1]Department of Neurology and Psychiatry,Assiut University Hospital,Assiut 71516,Egypt [2]Department of Psychiatry,Mansoura University,Mansoura 11001,Egypt [3]Department of Obstetrics and Gynecology,Mansoura University,Mansoura 11001,Egypt

出　　处：《World Journal of Psychiatry》2022年第8期1061-1075,共15页世界精神病学杂志

摘　　要：BACKGROUND Depression is a common problem in women in childbearing years due to burdens of motherhood and building a family.Few studies estimate the prevalence of antepartum depression compared to those in the postpartum period.AIM To estimate the prevalence and the severities of peripartum depression and major depressive disorder and their predictors.METHODS This is a longitudinal observation study.It included 200 women scoring≥13 with the Edinburgh Postpartum Depression Scale,indicating presence of symptoms of depression.They had a gestational age of≥6 wk and did follow-ups until the 10^(th) week to 12^(th) weeks postpartum.Information of women's reactions to life circumstances and stressors during the current pregnancy were gathered from answers to questions of the designed unstructured clinical questionnaire.Severities of depression,anxiety,and parenting stress were determined by the Beck Depression Inventory,State-Trait Anxiety Inventory for Adults,and Parenting Stress Index-Short Form,respectively.Psychiatric interviewing was done to confirm the diagnosis of major depression.Measuring the levels of triiodothronine(T3),thyroxine(T4),and thyroid stimulating hormone(TSH)was done in both antepartum and postpartum periods.RESULTS Out of 968(mean age=27.35±6.42 years),20.66%(n=200)of the patients had clinically significant symptoms of depression and 7.44%had major depression.Previous premenstrual dysphoria,post-abortive depression,and depression unrelated to pregnancy and were reported in 43%,8%,and 4.5%of the patients,respectively.Psychosocial stressors were reported in 15.5%of the patients.Antepartum anxiety and parenting stress were reported in 90.5%and 65%of the patients,respectively.Postpartum T3,T4,and TSH levels did not significantly differ from reference values.Regression analysis showed that anxiety trait was a predictor for antepartum(standardized regression coefficients=0.514,t=8.507,P=0.001)and postpartum(standardized regression coefficients=0.573,t=0.040,P=0.041)depression.Antepartum depression(

关 键 词：Peripartum depression Antepartum depression Postpartum depression Anxiety Edinburgh postpartum depression scale Parenting stress 

分 类 号：R749.4[医药卫生—神经病学与精神病学]