Barrett食管危险因素的研究进展  

Risk factors for Barrett’s esophagus:Recent advances

作　　者：马韶泽 陈鸿鑫 梁振东 祁兴顺 Shao-Ze Ma;Hong-Xin Chen;Zhen-Dong Liang;Xing-Shun Qi(Department of Gastroenterology,General Hospital of Northern Theater Command,Shenyang 110840,Liaoning Province,China;Graduate School of Dalian Medical University,Dalian 116044,Liaoning Province,China;Graduate School of Liaoning University of Traditional Chinese Medicine,Shenyang 110031,Liaoning Province,China)

机构地区：[1]北部战区总医院消化内科,辽宁省沈阳市110840 [2]大连医科大学研究生院,辽宁省大连市116044 [3]辽宁中医药大学研究生院,辽宁省沈阳市110031

出　　处：《世界华人消化杂志》2022年第14期605-613,共9页World Chinese Journal of Digestology

摘　　要：食管腺癌(esophageal adenocarcinoma,EAC)是西方国家最常见的食管恶性肿瘤.近年来,其发病率在我国也呈上升趋势.Barrett食管(Barrett’s esophagus,BE)是指食管下段的鳞状上皮被化生的柱状上皮所取代的病理现象.BE与EAC的发生密切相关.了解BE发生发展的相关危险因素对早期筛查和诊断BE及预防EAC具有重要意义.本文主要从临床、人口统计学、生活习惯和药物使用四个方面阐述BE的危险因素,以期为BE的临床防治提供更多有价值的科学依据.Esophageal adenocarcinoma(EAC)is the most common malignant tumor of the esophagus in the West.During the past few decades,its morbidity has been increasing in China.Barrett’s esophagus(BE)is defined as the replacement of normal squamous epithelium in the lower esophagus by metaplasia of columnar epithelium.BE is closely related to the occurrence of EAC.Knowledge regarding the risk factors for the occurrence and development of BE is of great significance for early screening and diagnosis of BE and prevention of EAC.In this paper,we review the clinical,demographics-related,lifestyle-related,and medications-related risk factors for BE to provide more valuable scientific evidence for the prevention and treatment of BE.

关 键 词：BARRETT食管 食管腺癌 胃食管反流病 危险因素 

分 类 号：R735.1[医药卫生—肿瘤]