“药-理-康”方案在血管性帕金森综合征临床治疗中的应用效果  

Application Effect of “Pharmacology-physics-health” Regimen in the Clinical Treatment of Vascular Parkinsonism

作　　者：肖朝飞 XIAO Chaofei(Pingxiang Ganxi Hospital,Jiangxi Province,Pingxiang 337099,China)

机构地区：[1]江西省萍乡赣西医院,江西萍乡337099

出　　处：《中国医学创新》2022年第22期152-157,共6页Medical Innovation of China

摘　　要：目的:探究“药-理-康”方案在血管性帕金森综合征临床治疗中的应用效果。目的在于完善血管性帕金森综合征的治疗方案,结合多种治疗措施以提高患者的治疗效果,从而为该疾病患者的临床治疗提供借鉴。方法:选取2019年3月-2021年3月萍乡赣西医院就诊的123例血管性帕金森综合征患者,按照随机数字表法将其分为对照组A(41例)、对照组B(41例)和观察组(41例)。对照组A采用常规疗法治疗,对照组B在常规疗法的基础上添加田七粉配合运动训练治疗,观察组采用“药-理-康”方案进行治疗,即常规药物、田七粉+重复经颅磁刺激(rTMS)+运动训练。比较三组治疗效果。结果:治疗后,三组日常生活、运动功能、精神行为评分均低于治疗前,且观察组均低于对照组A和对照组B(P<0.05)。治疗后,三组步宽、步长均长于治疗前,步速均大于治疗前,且观察组步宽、步长均长于对照组A和对照组B,步速大于对照组A和对照组B,差异均有统计学意义(P<0.05)。治疗后,对照组A和对照组B的步长比较,差异无统计学意义(P>0.05)。三组总有效率比较,差异有统计学意义(P<0.05)。治疗后,观察组CRP均低于对照组A和对照组B,DA均高于对照组A和对照组B,差异均有统计学意义(P<0.05)。结论:“药-理-康”方案治疗血管性帕金森综合征具有较高临床价值,不仅能改善患者的病情,还能提高其运动功能,降低炎症因子的表达,减少DA的丢失,从而促进治疗效果的提升。Objective:To explore the application effect of the “Pharmacology-physics-health” regimen in the clinical treatment of Vascular Parkinsonism.The purpose is to improve the treatment plan of vascular Parkinsonism,and combine a variety of treatment measures to improve the treatment effect of patients,so as to provide reference for the clinical treatment of patients with this disease.Method:A total of 123 patients with vascular Parkinsonism treated in Pingxiang Ganxi Hospital from March 2019 to March 2021 were selected,they were divided into control group A (41 cases),control group B (41 cases) and observation group (41 cases) according to random number table method.Control group A was treated with conventional therapy,control group B was treated with Tianqi Powder combined with exercise training on the basis of conventional therapy,observation group was treated with “Pharmacology-physics-health” regimen,namely,conventional drugs,Tianqi Powder + repeated transcranial magnetic stimulation (rTMS) + exercise training.The therapeutic effects of the three groups were compared.Result:After treatment,scores of daily life,motor function and mental behavior in the three groups were lower than those before treatment,and those in the observation group were lower than those in the control group A and B (P0.05).There was significant difference in total effective rate among three groups (P<0.05).After treatment,CRP in the observation group were lower than those in the control group A and B,and DA in the observation group were higher than those in the control group A and B,the differences were statistically significant (P<0.05).Conclusion:The “Pharmacology-physics-health” regimen has high clinical value in the treatment of vascular Parkinsonism.It can not only improve the patient’s condition,but also improve their motor function,reduce the expression of inflammatory factors,and reduce the loss of DA,thereby promoting treatment effect enhancement.

关 键 词：“药-理-康”方案 血管性帕金森综合征 帕金森病评定量表 步态变化 

分 类 号：R742.5[医药卫生—神经病学与精神病学]