贵州省黔东南地区少数民族居民饮食因素与代谢相关脂肪性肝病患病的关联分析  

Analysis of the association between dietary factors and the prevalence of metabolic-related fatty liver disease among ethnic minority residents in Qiandongnan,Guizhou Province

作　　者：徐子轩 刘磊磊 杨婷婷[1] 张林源 钟建琴 张燕[1] 徐德淦 洪峰[1] XU Zi-xuan;LIU Lei-lei;YANG Ting-ting;ZHANG Lin-yuan;ZHONG Jian-qin;ZHANG Yan;XU De-gan;HONG Feng(School of Public Health,the Key Laboratory of Environmental Pollution Monitoring and Disease Control,Ministry of Education,Guizhou Medical University,Guiyang,Guizhou 550025,China)

机构地区：[1]贵州医科大学公共卫生与健康学院,环境污染与疾病监控教育部重点实验室,贵州贵阳550025 [2]贵阳市疾病预防控制中心

出　　处：《现代预防医学》2022年第14期2553-2558,共6页Modern Preventive Medicine

基　　金：国家重点研发计划课题(2017YFC0907301);国家自然科学基金(82173566)。

摘　　要：目的了解贵州省黔东南地区少数民族居民代谢相关脂肪性肝病(metabolism-associated fatty liver disease,MAFLD)患病现状及与饮食因素间的关系。方法通过现场调查方式对贵州省黔东南地区30~79岁的10810名苗族侗族人群进行问卷调查和体格检查,二元logistic回归分析该地区MAFLD的饮食影响因素。结果当地人群MAFLD患病率为14.93%。腊肉摄入频率达到每月均吃(OR=1.28,95%CI:1.02~1.61)以及腌制蔬菜(OR=1.39,95%CI:1.11~1.73)和油茶(OR=1.35,95%CI:1.16~1.57)的摄入频率>2次/月时均可能会增加MAFLD的患病风险,而食用白酸汤(OR=0.76,95%CI:0.64~0.90)和蕨菜(OR=0.80,95%CI:0.65~0.99)的摄入频率>2次/月则均会降低MAFLD患病风险。结论过量频率的腊肉、腌制蔬菜以及油茶摄入可能会增加苗族侗族人群MAFLD的患病风险,而摄入适量的蕨菜、白酸汤则可能对该病有益。Objective To understand the prevalence of metabolism-associated fatty liver disease(MAFLD)and its relationship with dietary factors among ethnic minority residents in the Qiandongnan region of Guizhou Province.Methods On-site questionnaire survey and physical examination were conducted in 10810 Miao and Dong people aged 30 to 79 years in Qiandongnan,Guizhou Province.Results The prevalence of MAFLD in the local population was 14.93%.The frequency of cured meat intake up to monthly consumption(OR=1.28,95%CI:1.02-1.61)as well as the frequency of pickled vegetables(OR=1.39,95%CI:1.11-1.73)and oil-tea(OR=1.35,95%CI:1.16-1.57)intake>twice/month were likely to increase the risk of MAFLD,while the consumption of white sour soup(OR=0.76,95%CI:0.64-0.90)and fiddlehead fern(OR=0.80,95%CI:0.65-0.99)at a frequency of>twice/month might reduce the risk of MAFLD.Conclusion Excessive frequency of cured meat,pickled vegetables,and oil-tea intake may increase the risk of MAFLD in the Miao-Dong people,whereas moderate intake of fern and white sour soup may be beneficial.

关 键 词：代谢相关脂肪性肝病 少数民族 饮食 关联分析 

分 类 号：R575.5[医药卫生—消化系统]