关于肝内胆管癌的定义与中文命名的讨论  

Proposed definition and Chinese nomenclature of intrahepatic cholangiocarcinoma

作　　者：陈敏山[1] Chen Minshan(Department of Liver Surgery,Sun Yat-sen University Cancer Center,Guangdong Guangzhou 510060,China)

机构地区：[1]中山大学肿瘤防治中心肝脏外科,广东广州510060

出　　处：《腹部外科》2022年第4期233-235,240,共4页Journal of Abdominal Surgery

摘　　要：此文针对目前国内临床工作中“肝内胆管癌”的定义与中文命名进行了分析和讨论,通过对“ICC”“肝内胆管癌”和“肝胆管细胞癌”进行比较分析,结合国内外相关规范和指南,提出了命名的理由和建议.作者根据ICC的定义,指出ICC不宜称之为“肝内胆管癌”,认为“intrahepaticcholangiocarcinoma”的中文翻译应该为“肝内胆管细胞(上皮)癌”.由于ICC肿块型归属于肝脏,是原发性肝脏恶性肿瘤的一种,与“肝细胞癌”相并列,称之为“肝胆管细胞癌(ICC)”较为合理.而原ICC的另外两个亚型,管周浸润型和管内生长型,多涉及肝内胆管,治疗上与肿块型明显不同,归属于“胆管癌”更为合理,定义为“胆管恶性肿瘤”.从而,根据不同部位、生物学特性、治疗方式将原ICC的三个亚型分开,肿块型ICC定义为“肝胆管细胞癌”,管周浸润型和管内生长型属于“胆管癌”.强调肝胆管细胞癌具有独特的生物学特性、临床特点,应该作为一个独立的疾病进行诊断、分期和制订治疗策略和规范.The definition and Chinese nomenclature of intrahepatic cholangiocarcinoma(ICC)were proposed in clinical practices.Through comparing the definition of ICC,intrahepatic cholangiocarcinoma and hepatocholangiocarcinoma,the author introduced a nomenclature recommendation.Based on the definition of ICC,ICC should not be termed as intrahepatic cholangiocarcinoma and"intrahepatic cholangiocarcinoma"should be appreciated as intrahepatic cholangiocarcinoma(epithelial)carcinoma since ICC tumor type belongs to liver.As a kind of primary liver malignant tumor,it is in parallel with"hepatocellular carcinoma".Thus it is more reasonable to name it as hepatocholangiocarcinoma.Moreover,the other two subtypes of original ICC,i.e.periductal infiltrative type and intraductal growth type,are mostly correlated with intrahepatic bile duct and treatment strategies differ greatly from mass type.Therefore they should be better classified as cholangiocarcinoma and defined as bile duct malignant tumors.In short,three subtypes of original ICC are classified according to different locations,biological characteristics and treatment options,mass type ICC is defined as hepatic cholangiocarcinoma and periductal infiltrating and intraductal growth types belong to cholangiocarcinoma.It should be emphasized that hepatocholangiocarcinoma possesses unique biological and clinical characteristics and it should be diagnosed,staged and treated as an independent disease in the future.

关 键 词：命名法 肝内胆管癌 肝胆管细胞癌 

分 类 号：R73[医药卫生—肿瘤]