柴胡四金方联合脐针治疗浊毒内蕴型胆囊结石疗效观察  

Observation on the curative effect of Chaihu Sijin decoction combined with umbilical acupuncture on cholecystolithiasis with syndrome of turbid toxicity inter-accumulation

作　　者：兰慧 苏春芝[1] 万曼曼 苏飞[1] 张金丽[1] 孟宪鑫[1] 马伟 LAN Hui;SU Chunzhi;WAN Manman;SU Fei;ZHANG Jinli;MENG Xianxin;MA Wei(Hebei Provincial Hospital of Traditional Chinese Medicine,Shijiazhuang 050011,Hebei,China)

机构地区：[1]河北省中医院,河北石家庄050011

出　　处：《现代中西医结合杂志》2022年第13期1803-1807,共5页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：河北省中医药管理局科研计划项目(2020003)。

摘　　要：目的观察柴胡四金方联合脐针治疗浊毒内蕴型胆囊结石患者的临床疗效。方法选择2019年10月—2020年10月于河北省中医院肝病科门诊就诊的浊毒内蕴型胆囊结石患者70例为研究对象,按照随机数字表法分为治疗组和对照组。治疗组35例予柴胡四金方联合脐针治疗,对照组35例予金钱胆通颗粒治疗,2组均连续治疗12周。观察2组患者治疗前后中医症状积分及血清丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、γ-谷氨酰基转移酶(GGT)、Ca^(2+)、三酰甘油(TG)、总胆固醇(TC)、载脂蛋白A1(ApoA1)、载脂蛋白B(ApoB)水平变化,比较2组治疗12周后临床疗效。结果治疗后2组中医症状积分及血清AST、ALT、GGT、Ca^(2+)、TC、TG、ApoB水平均较治疗前明显降低(P均<0.05),且治疗组治疗后各指标均明显低于对照组(P均<0.05);治疗后2组ApoA1水平均较治疗前明显升高(P均<0.05),且治疗组ApoA1水平明显高于对照组(P<0.05)。治疗组总有效率为85.7%(30/35),高于对照组的68.5%(24/35),差异有统计学意义(P<0.05)。结论柴胡四金方联合脐针治疗能够改善浊毒内蕴型胆囊结石患者的临床症状、生化指标,使结石缩小甚至完全溶化,提高总体疗效。Objective It is to observe the clinical effect of Chaihu Sijin decoction combined with umbilical acupuncture in the treatment of patients with cholecystolithiasis with syndrome of turbid toxicity inter-accumulation.Methods A total of 70 patients with cholecystolithiasis with with syndrome of turbid toxicity inter-accumulation who were treated in the outpatient department of liver disease department of Hebei Provincial Hospital of Traditional Chinese Medicine from October 2019 to October 2020 were selected as the research objects,and divided into treatment group and control group according to the random number table method.35 cases in the treatment group were treated with Chaihu Sijin decoction combined with umbilical acupuncture,and 35 cases in the control group were treated with Jinqian Dantong granules,both groups were treated for 12 weeks.The changes of traditional Chinese medical symptom scores,and the levels of serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),gamma-glutamyltransferase(GGT),Ca^(2+),triacylglycerol(TG),total cholesterol(TC),apolipoprotein A1(ApoA1),apolipoprotein B(ApoB)before and after treatment were observed in the two groups,and the clinical curative effects were compared between the two groups after 12 weeks of treatment.Results After treatment,the traditional Chinese medical symptom scores,and the levels of serum AST,ALT,GGT,Ca^(2+),TC,TG,and ApoB in the two groups were significantly lower than those before treatment(all P<0.05),and each index in the treatment group after treatment was significantly lower than that in the control group(P<0.05).After treatment,the levels of ApoA1 in the two groups were significantly higher than those before treatment(both P<0.05),and the level of ApoA1 in the treatment group was significantly higher than that in the control group(P<0.05).The total effective rate in the treatment group was 85.7%(30/35),which was higher than that 68.5%(24/35)in the control group,and the difference was statistically significant(P<0.05).Conclusion Chaihu Sij

关 键 词：浊毒论 柴胡四金方 胆囊结石 浊毒内蕴型 脐针 

分 类 号：R575.62[医药卫生—消化系统]