Histamine H1 Receptor in Basal Forebrain Cholinergic Circuit:A Novel Target for the Negative Symptoms of Schizophrenia?  

作　　者：Shuangshuang Wu Chenshu Gao Feng Han Heming Cheng 

机构地区：[1]Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China [2]Key Laboratory of Cardiovascular and Cerebrovascular Medicine,School of Pharmacy,Nanjing Medical University,Nanjing 211166,China

出　　处：《Neuroscience Bulletin》2022年第5期558-560,共3页神经科学通报（英文版）

摘　　要：Schizophrenia is a common and severe mental disorder with a lifetime prevalence of~1%[1]Apart from the typical positive symptoms,such as hallucinations and delusions,which mainly make patients seek medication,60%-70%of patients are tortured by negative symptoms(e.g.apathy and alogia)and cognitive deficits that impose a long-term burden on patients[2].

关 键 词：SCHIZOPHRENIA PATIENTS MEDICATION 

分 类 号：R749.3[医药卫生—神经病学与精神病学]