亚健康状态动物模型研究现状分析  

Analysis on the current situation of the research on subhealth state animal model

作　　者：张翼东 王丹[2] 何清湖[1,3] 孙贵香 俞月[1] 邱丽婷 张千旭 ZHANG Ji-dong;WANG Dan;HE Qing-hu;SUN Gui-xiang;YU Yue;QIU Li-ting;ZHANG Qian-xu(Hunan University of Chinese Medicine,Changsha 410208,China;Hangzhou Normal University,Hangzhou 310108,China;Hunan University of Medicine,Huaihua 418000,China)

机构地区：[1]湖南中医药大学,长沙410208 [2]杭州师范大学,杭州310108 [3]湖南医药学院,怀化418000

出　　处：《中华中医药杂志》2022年第7期3745-3750,共6页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家中医药管理局项目(No.GZY-YZS-2019-45)。

摘　　要：动物模型是开展亚健康动物实验的基础。目前关于亚健康状态动物模型的研究还处于初期的探索阶段。文章从造模动物、模型种类、造模方法、模型评价4个方面对目前已开展的亚健康状态动物实验相关研究进行了系统梳理,并提出目前研究中存在着对亚健康概念认识不足、缺乏统一的造模方法与评价标准、心理亚健康与社会交往亚健康的动物模型尚待商椎的问题,并在此基础上提出建议,以期为后续研究的重点方向提供参考。Animal models are the basis for subhealth animal experiments.The current research on subhealth animal models is still in the initial stage of exploration.This article systematically sorts out the research related to subhealth animal experiments that have been carried out from four aspects:Modeling animals,model types,modeling methods,and model evaluations,and proposes that the current research has insufficient understanding of subhealth concepts,the model-building methods and evaluation standards are lack of uniformity,and mental subhealth and social communication subhealth animal models are still open for discussion.On this basis,suggestions are made in order to provide reference for the key directions of follow-up research.

关 键 词：亚健康 动物模型 现状 标准 

分 类 号：R-332[医药卫生]