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作 者:董莹盈 郭平[2] 任雪英[1] 赵建利[1] DONG Yingying;GUO Ping;REN Xueying;ZHAO Jianli(Department of Psychosomatic Disorders,Shaoxing Seventh People’s Hospital,Zhejiang Province,Shaoxing 312000,China;Department of Pediatric Internal Medicine,Shaoxing People’s Hospital,Zhejiang Province,Shaoxing 312000,China)
机构地区:[1]浙江省绍兴市第七人民医院心身障碍科,浙江绍兴312000 [2]浙江省绍兴市人民医院小儿内科,浙江绍兴312000
出 处:《妇儿健康导刊》2022年第8期11-14,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
基 金:浙江省医药卫生科技计划面上项目(2020KY987)。
摘 要:目的研究经颅直流电刺激(tDCS)联合认知治疗纠正注意缺陷多动障碍(ADHD)患儿行为问题的临床效果。方法选择2020年1月至2021年6月在绍兴市第七人民医院儿童心理科就诊并符合《精神障碍诊断与统计手册(第5版)》ADHD诊断标准患儿109例,应用随机数字表法分为观察组(55例,tDCS+认知治疗)、对照组(54例,口服盐酸哌甲酯缓释片+认知治疗),共观察8周。采用ADHD诊断量表父母版(ADHDRS-IV)、Achenbach儿童行为量表(CBCL)评估临床疗效,应用治疗副反应量表评价治疗中的不良反应。结果治疗8周末,两组的ADHD-RS-IV各项目和CBCL各项目评分低于治疗前,且观察组的ADHD-RS-IV各项目和CBCL各项目评分低于对照组,差异均有统计学意义(P<0.05);观察组发生1例不良反应,对照组发生7例,差异有统计学意义(P<0.05)。结论tDCS联合认知治疗的临床效果优于盐酸哌甲酯缓释片联合认知治疗,且安全性高。Objective To study the clinical effect of transcranial direct current stimulation(tDCS)combined with cognitive therapy in correcting behavioral problems in children with attention deficit hyperactivity disorder(ADHD).Methods A total of 109 children who met the diagnostic criteria of ADHD in the Diagnostic and Statistical Manual of Mental Disorders(5th edition)were selected from January 2020 to June 2021 in the Child Psychology Department of Shaoxing Seventh People’s Hospital.The children were divided into the observation group(55 cases,tDCS+cognitive therapy)and the control group(54 cases,Methylphenidate Hydrochloride Sustained Release Tablets+cognitive therapy)by random number table method for 8 weeks of observation.The clinical efficacy was evaluated by ADHD rating scale IV(ADHD-RS-IV)and Achenbach’s Child Behavior Checklist(CBCL).The treatment emergent symptom scale was used to evaluate the adverse reactions.Results After 8 weeks of treatment,the scores of ADHD-RS-IV and CBCL items in both groups were lower than those before treatment,and the scores of ADHD-RS-IV and CBCL items in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).There was 1 case adverse reaction in the observation group and 7 cases in the control group,and the difference was statistically significant(P<0.05).Conclusion The clinical effect of tDCS combined with cognitive therapy is better than that of Methylphenidate Hydrochloride Sustained Release Tablets combine d with cognitive therapy,and the safety is high.
关 键 词:经颅直流电刺激 儿童注意缺陷多动障碍 行为问题 安全性
分 类 号:R749.4[医药卫生—神经病学与精神病学]
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