颅内血管支架置入在颅内动脉狭窄患者中的应用  

Clinical study on endovascular treatment of intracranial arterial stenosis

作　　者：罗小辉 廖余平 蒋蓓蓓 LUO Xiaohui;LIAO Yuping;JIANG Beibei(Department of Cerebrovascular Disease,People′s Hospital of Xinyu City,Jiangxi Province,Xinyu,338000,China)

机构地区：[1]江西省新余市人民医院脑血管病科,江西新余338000

出　　处：《中国当代医药》2022年第22期74-76,80,共4页China Modern Medicine

基　　金：江西省新余市科技计划项目(20213090821)。

摘　　要：目的探讨颅内血管支架置入在颅内动脉狭窄患者中的应用效果。方法回顾性分析2018年1月至2020年6月新余市人民医院收治的90例颅内动脉狭窄患者的临床资料,依据治疗方法不同将其分为支架置入组(n=49)及药物治疗组(n=41)。药物治疗组口服阿司匹林肠溶片及氯吡格雷,支架置入组在药物治疗组的基础上行颅内血管支架置入。比较两组患者的美国国立卫生研究院卒中量表(NIHSS)评分、并发症总发生率及复发率。结果支架置入组患者治疗后的NIHSS评分为(8.14±0.98)分,低于药物治疗组的(15.46±2.20)分,差异有统计学意义(P<0.05)。支架置入组患者的并发症总发生率为4.08%,低于药物治疗组的21.95%,差异有统计学意义(P<0.05)。支架置入组患者的复发率为4.08%,低于药物治疗组的26.83%,差异有统计学意义(P<0.05)。结论与口服药物治疗相比,采用颅内血管支架置入治疗颅内动脉狭窄可获得较好的临床效果,能够有效减轻神经功能受损情况,且并发症少,复发率低,具有较高的安全性,值得推广应用。Objective To investigate the clinical effect of endovascular treatment for intracranial arterial stenosis.Methods The clinical data of 90 patients with intracranial artery stenosis admitted to Xinyu People′s Hospital from January 2018 to June 2020 were retrospectively analyzed.According to different treatment methods,they were divided into stent implantation group(n=49)and drug treatment group(n=41).The drug treatment group received Aspirin Enteric-Coated Tablets and Clopidogrel orally,and the stent implantation group received intracranial vascular stent implantation on the basis of the drug treatment group.National Institutes of Health stroke scale(NIHSS)score,total incidence of complications and recurrence rate were compared between the two groups.Results The NIHSS score after treatment in the stent implantation group([8.14±0.98]points)was lower than that in the drug treatment group([15.46±2.20]points),and the difference was statistically significant(P<0.05).The total incidence of complications in the stent implantation group(4.08%)was lower than that in the drug treatment group(21.95%),the difference was statistically significant(P<0.05).The recurrence rate of patients in the stenting group(4.08%)was lower than that in the drug treatment group(26.83%),and the difference was statistically significant(P<0.05).Conclusion Compared with oral drug therapy,intracranial vascular stent implantation in the treatment of intracranial artery stenosis can achieve better clinical effect,can effectively reduce the neurological impairment,and has fewer complications,lower recurrence rate,and high efficacy,which is worthy of promotion and application.

关 键 词：颅内动脉狭窄 血管内介入手术 阿司匹林肠溶片 氯吡格雷 神经功能缺损评分 并发症 

分 类 号：R743[医药卫生—神经病学与精神病学]