老年人短暂性脑缺血发作危险因素与预后  

Risk factors and prognosis of transient ischemic attack in the elderly

作　　者：娄秋英[1] 罗春香[1] LOU Qiuying;LUO Chunxiang(Department of Neurology,the Second Affiliated Hospital of Nanchang University,Jiangxi Province,Nanchang330006,China)

机构地区：[1]南昌大学第二附属医院神经内科,江西南昌330006

出　　处：《中国当代医药》2022年第22期77-80,共4页China Modern Medicine

基　　金：江西省卫生计生委科技计划项目(20155263);江西省卫生计生委科技计划项目(20175256)。

摘　　要：目的探讨老年人短暂性脑缺血(TIA)发作危险因素与预后。方法回顾性分析2018年9月至2021年9月南昌大学第二附属医院收治的84例TIA患者临床资料,按照年龄分为中青年组(年龄≤65岁,34例)和老年组(年龄>65岁,50例),收集两组患者一般资料,血脂、血糖指标水平及预后,采用多因素logistic回归分析老年人TIA的危险因素。结果老年组糖尿病比率(44.00%)高于中青年组(14.71%),差异有统计学意义(P<0.05)。老年组三酰甘油(TG)、空腹血糖(FBG)、胆固醇(CHO)及低密度脂蛋白胆固醇(LDL-C)水平高于中青年组,高密度脂蛋白胆固醇(HDL-C)水平低于中青年组,差异有统计学意义(P<0.05)。logistic回归分析显示,糖尿病(β=1.334,OR=1.982,95%CI=1.318~2.984)、CHO(β=3.853,OR=1.748,95%CI=1.361~2.937)、HDL-C(β=2.841,OR=2.328,95%CI=1.472~3.386)、LDL-C(β=1.596,OR=1.853,95%CI=1.653~2.740)、FBG(β=0.967,OR=1.263,95%CI=1.037~3.194)是老年人TIA的独立危险因素(P<0.05)。老年组病后90 d内严重血管事件发生率高于中青年组,差异有统计学意义(P<0.05)。结论糖尿病、CHO、HDL-C、LDL-C及FBG是老年TIA发生的高危因素,应尽早采取对症治疗存在危险因素的老年TIA患者,改善预后。Objective To explore the risk factors and prognosis of transient ischemic attack(TIA)in the elderly.Methods The clinical data of 84 patients with TIA reated in the Second Affiliated Hospital of Nanchang University from September 2018 to September 2021 were analyzed retrospectively.They were divided into young and middle-aged group(≤65 years old,n=34)and elderly group(>65 years old,n=50).The general data,blood lipid,blood glucose index level and prognosis of the two groups were collected,logistic regression was used to analyze the risk factors of TIA in the elderly.Results The ratio of diabetes in the elderly group(44.00%)was higher than that in the young and middle-aged group(14.71%),and the difference was statistically significant(P<0.05).The levels of triglyceride(TG),fasting blood glucose(FBG),cholesterol(CHO)and low-density lipoprotein cholesterol(LDL-C)in the elderly group were higher than those in the young and middle-aged group,and the levels of high-density lipoprotein cholesterol(HDL-C)were lower than those in the young and middle-aged group(P<0.05).Logistic regression analysis showed diabetes mellitus(β=1.334,OR=1.982,95%CI=1.318-2.984),CHO(β=3.853,OR=1.748,95%CI=1.361-2.937),HDL-C(β=2.841,OR=2.328,95%CI=1.472-3.386),LDL-C(β=1.596,OR=1.853,95%CI=1.653-2.740),FBG(β=0.967,OR=1.263,95%CI=1.037-3.194)were independent risk factors for transient ischemic attack in the elderly(P<0.05).The incidence of serious vascular events within 90 days after the disease in the elderly group was higher than that in the young and middle-aged group,and the difference was statistically significant(P<0.05).Conclusion Diabetes,CHO,HDL-C,LDL-C and FBG are the high risk factors of TIA.Early treatment should be taken to improve the prognosis of patients with TIA.

关 键 词：短暂性脑缺血 危险因素 预后 

分 类 号：R743.3[医药卫生—神经病学与精神病学]