儿童症状性癫痫MRI诊断分析  

MRI features of symptomatic epilepsy in children

作　　者：肖波涛[1] 高斌 曹建华[1] 许锐 邓伟 XIAO Bo-tao;GAO Bin;CAO Jian-hua;无(Departmentof Radiology,Huanggang Maternal and Child Health Hospital,Huanggang 438000 China;Department of Radiology,Wuhan Jiangxia Hospital,Hubei Wuhan 430000,China;Department of Laboratory,Huanggang Maternal and Child Health Hospital,Huanggang 438000 China)

机构地区：[1]黄冈市妇幼保健院放射科,湖北黄冈438000 [2]武汉市江夏医院放射科,湖北武汉430000 [3]黄冈市妇幼保健院检验科,湖北黄冈438000

出　　处：《中国实验诊断学》2022年第6期877-880,共4页Chinese Journal of Laboratory Diagnosis

基　　金：湖北省卫生健康委员会科研项目(WJ2019F131)。

摘　　要：目的 分析儿童症状性癫痫患儿的MRI征象。方法 选取2018年10月-2020年9月收治的130例疑为症状性癫痫患儿作为研究对象,所有患儿均行MRI检查,以术中监测结果为金标准,评估MRI的诊断效能,计算MRI诊断符合度、灵敏度、特异度,并分析MRI的检查结果。结果 术中监测结果显示病灶异常的有116例,无异常的有14例;以术中监测结果为金标准,MRI检查时发现病灶异常的有114例,无异常的有16例;MRI诊断符合度、灵敏度、特异度为92.31%(120/130),94.83%(110/116)、71.43%(10/14);经MRI检查异常的114例儿童症状性癫痫患儿中部分性发作88例,全面性发作23例,发作类型不明确3例,发作病因以感染性病变、颅内肿瘤、脑软化灶等为主;经MRI检查异常的114例儿童症状性癫痫患儿中病灶位于左侧56例,右侧39例,双侧19例;病灶多发于颞叶及额叶间,且临床多表现为部分性发作;114例症状性癫痫MRI异常患儿,T1加权成像呈低信号或者稍高信号,T2加权成像呈等信号或者稍高信号;其中感染性病变引发的症状性癫痫患儿T1WI呈稍低信号,T2WI呈高信号;颅内出血引发的症状性癫痫患儿T1WI、T2WI均呈等信号。结论 儿童症状性癫痫患儿发作形式多样,且以部分性发作为主,MRI可对癫痫病灶进行有效定位,是评估儿童症状性癫痫的有效方案。Objective To analyze the MRI features of children with symptomatic epilepsy.Methods 130children with suspected symptomatic epilepsy in our hospital from October 2018to September 2020were selected as the research objects.All children underwent MRI examination.The intraoperative monitoring results were taken as the gold standard to evaluate the diagnostic efficiency of MRI,calculate the diagnostic coincidence,sensitivity and specificity of MRI,and analyze the results of MRI examination.Results Intraoperative monitoring results showed that 116cases had abnormal lesions and 14cases had no abnormal lesions;with intraoperative monitoring results as the gold standard,114cases had abnormal lesions and 16cases had no abnormal lesions;the diagnostic coincidence,sensitivity and specificity of MRI were 92.31%(120/130),94.83%(110/116)and 71.43%(10/14);114cases of children with symptomatic epilepsy were abnormal by MRI 88cases were classified seizures,23cases were generalized seizures,and 3cases were of unclear seizure type.The main causes of seizures were infectious lesions,intracranial tumors and encephalomalacia.Among the114cases of children with symptomatic epilepsy,56cases were located on the left side,39cases on the right side and 19cases on both sides;The lesions were mainly located in the temporal lobe and frontal lobe,and most of them were clinically partial attacks;In 114children with symptomatic epilepsy with abnormal MRI,T1-weighted imaging showed low signal intensity or slightly high signal intensity,and T2-weighted imaging showed isointensity or slightly high signal intensity;among them,children with symptomatic epilepsy caused by infectious lesions showed slightly low signal intensity on T1WI and high signal intensity on T2WI;children with symptomatic epilepsy caused by intracranial hemorrhage showed isointensity on T1WI and T2WI.Conclusion Children with symptomatic epilepsy have a variety of seizures,and most of them are partial seizures.MRI can effectively locate the epileptic focus,which is an effective schem

关 键 词：磁共振 儿童 症状性癫痫 诊断效能 定位 

分 类 号：R742.1[医药卫生—神经病学与精神病学]