Elementary school comprehensive intervention and myopia development:the Wenzhou Epidemiology of Refraction Error Study  

作　　者：Dan-Dan Jiang Jie Chen Frank Thorn Guang-Yun Mao Chun-Chun Li Zhong Lin Balamurali Vasudevan Xiao-Qiong Huang Yan-Yan Chen 

机构地区：[1]The Eye Hospital of Wenzhou Medical University,Wenzhou 325000,Zhejiang Province,China [2]Deptartment of Brain&Cognitive Sciences,MIT Cambridge,Cambridge,MA 02139,USA [3]School of Public Health,Wenzhou Medical University,Wenzhou 325000,Zhejiang Province,China [4]College of Optometry,MidWestern University,Glendale,AZ 84729,USA

出　　处：《International Journal of Ophthalmology(English edition)》2022年第8期1363-1369,共7页国际眼科杂志（英文版）

基　　金：Supported by National Natural Science Foundation of China(No.81873683)。

摘　　要：AIM:To investigate the effects of school-basedcomprehensive intervention on myopia development inelementary school children.METHODS:As a part of the Wenzhou Epidemiologyof Refraction Error Study,there were 1524 participatingelementary students(730 girls,47.9%)in grades 1 to3 from three campuses of one school,aged 7.3±0.9y,who were examined twice every year for a 2.5y follow upperiod.Comprehensive intervention and other reminderswere given at school every semester for the interventiongroup.The control group did not receive comprehensiveintervention and did not have reminders of it.RESULTS:There were 651 students in the interventiongroup[mean age 7.3±0.9y;294(45.2%)girls]and 737students in the control group[mean age 7.2±0.9y;346(46.9%)girls].Overall mean myopia progression duringthe 2.5y follow-up was-0.49±1.04 diopters(D)in theintervention group and-0.65±1.08 D in the control group(P=0.004).The majority that not get myopia at baselinespherical equivalent(SE≤-1.0 D).Their mean myopiaprogression during the 2.5y follow-up was-0.37±0.89 Din the intervention group and-0.51±0.93 D in the controlgroup(27.5%reduction,P=0.009);Overall,mean axiallength elongation was less in the intervention group(0.56±0.32 mm)than in the control group(0.61±0.38 mm,10.5%reduction,P=0.009).The percentage of close reading distance(<30 cm)in the intervention group was less than in the control group(73.4%vs 76.2%,P<0.001),the percentage of everyday perform eye exercises in the intervention group was more than in the control group(27.8%vs 20.7%,P<0.001)30mo later.CONCLUSION:The comprehensive intervention program at elementary school has a significant alleviating effect on myopia progression for children during the 2.5y follow-up,especially for those non-myopia at baseline.

关 键 词：myopia progression axial length comprehensive intervention school children 

分 类 号：R778.11[医药卫生—眼科]