Magnetic Ti_(3)C_(2)T_(x)/Fe_(3)O_(4)/Ag substrate for rapid quantification of trace sulfonamides in aquatic products by surface enhanced Raman spectroscopy  

作　　者：Zhongning Yu Lu Huang Zhuomin Zhang Gongke Li 

机构地区：[1]School of Chemistry,Sun Yat-sen University,Guangzhou 510275,China

出　　处：《Chinese Chemical Letters》2022年第8期3853-3858,共6页中国化学快报（英文版）

基　　金：financially supported by the National Natural Science Foundation of China(Nos.22074161 and 21976213);Guangdong Basic and Applied Basic Research Foundation(No.2019A1515010107);the Science and Technology Planning Project of Guangzhou City(No.202102080167);the Research and Development Plan for Key Areas of Food Safety in Guangdong Province of China(No.2019B020211001);the National Key Research and Development Program of China(No.2019YFC1606101);the State Key Program of National Natural Science of China(No.22134007)。

摘　　要：Surface-enhanced Raman scattering(SERS)spectroscopy has been employed as a rapid analysis technology for food security inspection recently.Nowadays,it is still a great challenge to rapidly quantify multiple trace antibiotics potentially abused in aquaculture industry.In this work,a magnetic Ti_(3)C_(2)T_(x)/Fe_(3)O_(4)/Ag substrate was prepared for the development of a reliable rapid SERS quantification method for multiple trace sulfonamides in aquatic products.This magnetic substrate had good uniformity,reproducibility,stability and SERS activity.Moreover,this substrate could integrate the magnetic separation-enrichment and matrix clean-up without cross contamination,which endowed it with good selectivity and antiinterference capability during real sample analysis.The electromagnetic enhancement and chemical enhancement mechanism of this magnetic substrate were studied in detail to reveal its good separationenrichment performance and SERS activity.Finally,a rapid SERS quantification method was established and practically applied for trace phthalic sulfathiazole(PST)and silver sulfadiazine(SSD)in aquatic products by using Ti_(3)C_(2)T_(x)/Fe_(3)O_(4)/Ag magnetic substrates.Trace PST and SSD could be actually detected and quantified as 55.9μg/kg and 64.0μg/kg in aquatic products,respectively.Good recoveries of 83.9%-116%with relative standard deviations(RSDs)of 0.5%-3.2%for PST and 80.2%-102%with RSDs of 1.3%-5.8%for SSD were obtained.This work proposed an efficient and reliable method for rapid quantification of trace multiple sulfonamides in complex aquatic samples during food security inspection.

关 键 词：Magnetic substrate Ti_(3)C_(2)T_(x)/Fe_(3)O_(4)/Ag Rapid SERS quantification Trace sulfonamides Aquatic samples 

分 类 号：TS254.7[轻工技术与工程—水产品加工及贮藏工程] O657.37[轻工技术与工程—食品科学与工程]