Acuros XB算法和AAA算法在鼻咽癌容积旋转调强计划中的剂量学差异研究  

Dosimetric difference of Acuros XB and AAA algorithm for nasopharyngeal carcinoma volume modulated arc therapyc radiotherapy planning

作　　者：李毅[1] 李芳[1] 李宇星 苏王辉[1] 何赟[1] 马红兵[1] LI Yi;LI Fang;LI Yuxing;SU Wanghui;HE Yun;MA Hongbing(The Second Affiliated Hospital of Xi'an Jiaotong University,Shaanxi Xi'an 710004,China)

机构地区：[1]西安交通大学第二附属医院,陕西西安710004

出　　处：《现代肿瘤医学》2022年第17期3213-3217,共5页Journal of Modern Oncology

基　　金：陕西省重点研发计划(编号:2020SF-027)。

摘　　要：目的:比较Acuros XB算法和AAA算法在鼻咽癌容积旋转调强计划中的剂量学差异。方法:在Eclipse计划系统中建立非均质模型并设计单野测试计划,比较Acuros XB、AAA算法百分深度剂量和离轴剂量的差异。回顾性选取10例鼻咽癌容积旋转调强病例计划,分别采用Acuros XB、AAA算法计算剂量,对比两种算法在实际病例中的剂量学差异。结果:在非均质模型中,两种算法的百分深度差异最大为11.1%,离轴剂量最大差异为10.96%,在与水的交界处产生剂量突变。病例测试中,Acuros XB算法的危及器官和靶区剂量均略低于AAA算法,危及器官中晶体的差异最大为16%,靶区95%的剂量差异为1.05%。结论:对于鼻咽癌容积旋转调强放疗计划,在硬件条件和时间允许的情况下,建议选择较为精准的Acuros XB算法。Objective:To compare the dosimetric differences between Acuros XB algorithm and AAA algorithm in volume rotation intensity modulation plan of nasopharyngeal carcinoma.Methods:The heterogeneous model was established in the eclipse planning system,and the single field test plan was designed to compare the difference between the percent depth dose and off-axis dose of Acuros XB and AAA algorithms.Ten cases of nasopharyngeal carcinoma were selected retrospectively.Acuros XB and AAA algorithms were used to calculate the dose respectively.The dosimetric differences between the two algorithms in actual cases were compared.Results:In the phantom test,the maximum difference of the percentage depth difference between the two algorithms was 11.1%,and the maximum offaxial dose difference was 10.96%,in the heterogeneous material.And a dose mutation was found at the junction with water.In the patient cases tests,both the organ at risk(OAR)and the target's doses calculated by Acuros XB were slightly lower than the AAA algorithm.The difference of the lens was 16%,which was the the maximum difference,and the D_(95) dose difference of the target was 1.05%.Conclusion:The Acuros XB algorithm is recommended for the nasopharyngeal cancer volume modulated arc therapy radiotherapy plan if the hardware conditions and time are sufficient.

关 键 词：Acuros XB算法 各项异性解析算法 鼻咽癌 

分 类 号：R739.62[医药卫生—肿瘤]