Ultrasound delivery of Chinese rhubarb promotes early recovery of gastrointestinal function after gastrectomy:a prospective randomized controlled study  

作　　者：Hengbo Jia Shaofeng Wang Lujun Shen Jun You Fan Yang Masanobu Abe Yingying Xu Liang Zong 

机构地区：[1]Department of Nursing,Changzhi People's Hospital,The Afiliated Hospital of Changzhi Medical College,Changzhi,Shanxi Province [2]Department of Gastrointestinal Surgery,Changzhi People's Hospital,The Afiliated Hospital of Changzhi Medical College,Changzhi,Shanxi Province [3]Department of Gastroenterology,Changzhi People's Hospital,The Afiliated Hospital of Changzhi Medical College,Changzhi,Shanxi Province [4]Department of Gastointestinal Surgery,The Frst Afiliated Hospital of Xiamen University,Xiamen,Fujian Province [5]Department of Central Laboratory,Changzhi People's Hospital,The Afilated Hospital of Changzhi Medical College,Changzhi,Shanxi Province,China [6]Division for Health Senice Promotion,University of Tokyo Hospital,Tokyo,Japan [7]Department of Gastrointestinal Surgery,Yzheng People's Hospital,Cinical Medical College,Yangzhou University,Yangzhou,Jiangsu Provinoe,China

出　　处：《Journal of Bio-X Research》2021年第3期130-135,共6页生物组学研究杂志（英文）

基　　金：This work was supported by the Jiangsu Natural Science Foundation(No.BK20180274,to LZ).

摘　　要：Objective: Chinese rhubarb is a promising Chinese medicine for the promotion of gastrointestinal function. This study was conducted to investigate the safety and efficacy of Chinese rhubarb administered via ultrasound delivery in promoting the early recovery of gastrointestinal function after gastrectomy.Methods: In this prospective randomized controlled study, 100 patients who were scheduled to undergo total or subtotal gastrectomy in Changzhi People’s Hospital or Subei People’s Hospital from August 2017 to January 2018 were recruited. These patients were randomly assigned into two equal groups before surgery: 50 in the experimental (Chinese rhubarb) group, and 50 in the control (routine nursing) group. After surgery, time to flatus, bowel movement, clear liquid diet, and removal of nasogastric tube were recorded and analyzed. In addition, postoperative pain, postoperative bowel movement-related complications, and postoperative hospital stay duration were also recorded and analyzed. The study was approved by The protocol was approved by the Institutional Review Board of Changzhi People’s Hospital and Subei People’s Hospital on July 1, 2017 and registered with the Chinese Clinical Trial Registry on December 17, 2018 (registration number: ChiCTR1800020143).Results: Time to flatus (control group 85.68±22.00 hours vs experimental group 73.06±23.42 hours;P=0.007), bowel movement (5.52±1.56 vs 4.40±1.21 days;P<0.001), clear liquid diet (6.72±1.16 vs 6.22±1.28 days;P=0.044), and removal of nasogastric tube (6.30±1.52 vs 5.65±1.58 days;P=0.044) were significantly shorter in the experimental group compared with the control group, as was the postoperative hospital stay duration (14.30±3.46 vs 12.86±1.36 days;P=0.006). In addition, better pain relief (P=0.003) and a lower incidence of postoperative bowel movement-related complications (6 vs 21;P=0.001) were noted in the experimental group.Conclusion: Ultrasound delivery of Chinese rhubarb is useful to promote the early recovery of gastrointestinal functio

关 键 词：Chinese rhubarb GASTRECTOMY gastrointestinal function randomized controlled trial ultrasound delivery 

分 类 号：R57[医药卫生—消化系统]