胃肠道分化极好腺癌的诊断思考  

Consideration of diagnosing extremely well differentiated adenocarcinoma of gastrointestinal tract

作　　者：周炜洵[1] 陈杰[1] Zhou Weixun;Chen Jie(Department of Pathology,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院病理科,北京100730

出　　处：《中华病理学杂志》2022年第8期693-695,共3页Chinese Journal of Pathology

摘　　要：对于胃肠道分化极好的腺癌, 近年来涌现出一些诊断名称, 它们含义有重叠也有差别, 需辨析后准确应用。低异性度分化型腺癌和超高分化腺癌, 是一组分化好、细胞异型性小的腺癌的总称, 包含多种组织学类型, 诊断时建议应尽量列出具体的组织学类型, 不单独使用"低异性度分化型腺癌"或"超高分化腺癌"作为完整的诊断。这类腺癌细胞异型性小, 需观察结构异型性进行诊断, 同时注意和反应性改变、低级别异型增生、黏膜内陷等病变的鉴别。For gastrointestinal adenocarcinoma with excellent differentiation,some diagnostic names have emerged in recent years,which have overlapping and different meanings.Low-grade well differentiated adenocarcinoma and very well differentiated adenocarcinoma are terms for a group of adenocarcinomas with good differentiation and little cellular atypia,including a variety of histological types.It is suggested that specific histological types should be listed as far as possible in diagnosis,instead of using"low-grade well differentiated adenocarcinoma"or"very well differentiated adenocarcinoma"as a complete diagnosis.This kind of adenocarcinomas may lack cellular pleomorphism,so it is necessary to observe the structural atypia for diagnosis.At the same time,attention should be paid to the differentiation of reactive changes,low grade dysplasia,epithelial misplacement and other lesions.

关 键 词：高分化腺癌 诊断名称 细胞异型性 异型增生 组织学类型 胃肠道 分化型 低级别 

分 类 号：R735[医药卫生—肿瘤]