康复运动训练合经颅直流电刺激对帕金森病患者步行功能、平衡功能和认知功能的影响  

Effects of Rehabilitation Exercise Training Combined with Transcranial Direct Current Stimulation on Walking Function,Balance Function and Cognitive Function in Patients with Parkinson’s Disease

作　　者：洪东好[1] 祝善尧[1] 陈海燕[1] 许敏[1] 余小非 杨卫民[2] HONG Dong-hao;ZHU Shan-yao;CHEN Hai-yan;XU Min;YU Xiao-fei;YANG Wei-min(Department of Internal Medicine-Neurology,Chaohu Hospital Affiliated to Anhui Medical University,Hefei,Anhui,238000,China;Department of Internal Medicine-Neurology,The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui,230022,China)

机构地区：[1]安徽医科大学附属巢湖医院神经内科,安徽合肥238000 [2]安徽医科大学第一附属医院神经内科,安徽合肥230022

出　　处：《现代生物医学进展》2022年第13期2575-2578,2563,共5页Progress in Modern Biomedicine

基　　金：安徽省自然科学基金项目(1908085QH322)。

摘　　要：目的:探讨康复运动训练联合经颅直流电刺激(t DCS)对帕金森病(PD)患者步行功能、平衡功能和认知功能的影响。方法:选择2018年5月至2021年5月期间我院收治的PD患者60例,根据计算机生成数据随机分为对照组和研究组各30例。对照组患者接受康复运动训练,研究组患者接受康复运动训练联合t DCS,两组均治疗两周。对比两组步行功能、平衡功能、肢体功能、认知功能和生活自理能力的变化。结果:研究组治疗后步速、步频、步宽高于对照组(P<0.05)。研究组治疗后Berg平衡量表(BBS)评分高于对照组(P<0.05)。研究组治疗后蒙特利尔认知评估量表(MoCA)各项评分及总分高于对照组(P<0.05)。研究组治疗后统一帕金森病评价量表第三部分(UPDRS-Ⅲ)评分低于对照组,改良Barthel指数(MBI)评分高于对照组(P<0.05)。结论:PD患者经康复运动训练联合t DCS治疗,运动和非运动障碍均可得到显著改善,生活自理能力提高,临床应用价值较高。Objective:To investigate the effects of rehabilitation exercise training combined with transcranial direct current stimulation(t DCS) on walking function,balance function and cognitive function in patients with Parkinson’s disease(PD).Methods:60patients with PD who were treated from May 2018 to May 2021 were selected.According to the computer-generated data,they were randomly divided into control group and study group,with 30 cases in each group.The patients in the control group received rehabilitation exercise training,and the patients in the study group received rehabilitation exercise training combined with t DCS,both groups were treated for two weeks.The walking function,balance function,limb function,cognitive function and self-care ability of the two groups were compared.Results:After treatment,the step speed,step frequency and step width in the study group were higher than those in the control group(P<0.05).After treatment,the score of Berg Balance Scale(BBS) in the study group was higher than that in the control group(P<0.05).The scores and total scores of Montreal Cognitive Assessment Scale(MoCA) in the study group after treatment were higher than those in the control group(P<0.05).After treatment,the score of the third part of the Unified Parkinson’s disease evaluation scale(UPDRS-Ⅲ) in the study group was lower than that in the control group,and the score of the modified Barthel Index(MBI) was higher than that in the control group(P<0.05).Conclusion:The patients with PD treated with rehabilitation exercise training combined with t DCS can significantly improve motor and non motor disorders,improve self-care ability,and which have high clinical value.

关 键 词：康复运动训练 经颅直流电刺激 帕金森病 步行功能 平衡功能 认知功能 

分 类 号：R742.5[医药卫生—神经病学与精神病学] R493[医药卫生—临床医学]