内镜下聚桂醇联合组织胶对食管胃静脉曲张出血近远期疗效的影响  

Effect of endoscopic lauryl alcohol combined with tissue glue on short-term and long-term efficacy of esophageal-gastric varices bleeding

作　　者：李慧国 李涛[1] 万祥祥 田爱 LI Huiguo;LI Tao;WAN Xiangxiang;TIAN Ai(Department of Gastroenterology,Nanchang Ninth Hospital,Nanchang,Jiangxi,330029,China)

机构地区：[1]南昌市第九医院消化内科,江西南昌330029

出　　处：《当代医学》2022年第20期52-55,共4页Contemporary Medicine

摘　　要：目的 探究内镜下聚桂醇联合组织胶对食管胃静脉曲张出血(EGVB)近远期疗效的影响。方法 回顾性分析2017年5月至2019年5月南昌市第九医院消化内科收治的116例EGVB患者的临床资料,按治疗方式不同分为A组(n=60)与B组(n=56)。A组采用内镜下聚桂醇联合组织胶进行治疗,B组采用单纯内镜下使用组织胶进行治疗,比较两组止血成功率,近远期再出血情况,治疗1、3个月及1年后临床疗效及并发症发生情况。结果 两组止血成功率、近期再出血率比较差异均无统计学意义;A组远期再出血率显著低于B组,差异有统计学意义(P<0.05)。治疗1个月、3个月及1年,两组治疗总有效率比较差异均无统计学意义。A组术后并发症发生显著低于B组,差异有统计学意义(P<0.05)。结论 单纯使用内镜下组织胶和采用内镜下聚桂醇联合组织胶治疗EGVB疗效均显著,均具有较高的止血成功率并控制近期再出血率,但采用内镜下聚桂醇联合组织胶能更有效降低EGVB患者远期再出血率,且并发症较少,有助于改善患者预后,值得临床推广应用。Objective To investigate the effect of lauryl alcohol combined with tissue glue on the short-term and long-term efficacy of esophageal-gastric varices bleeding(EGVB) under endoscopy. Methods The clinical data of 116 EGVB patients admitted to the Department of Gastroenterology, Nanchang Ninth Hospital from May 2017 to May 2019 were retrospectively analyzed, and they were divided into group A(n=60) and group B(n=56) according to the different treatment methods. Group A was treated with lauryl alcohol combined with tissue glue under endoscopy,and group B was treated with tissue glue under endoscopy alone, the success rate of hemostasis, the rebleeding situation in the short-term and longterm, the clinical effective rate after 1, 3 months and 1 year of treatment and the incidence of complications were compared between the two groups. Results There was no significant difference in the success rate of hemostasis and the short-term rebleeding rate between the two groups;the long-term rebleeding rate in group A was significantly lower than that in group B, and the difference was statistically significant(P<0.05). After 1, 3months and 1 year of treatment, there was no significant difference in the total clinical effective rate between the two groups. The incidence of postoperative complications in group A was significantly lower than that in group B, and the difference was statistically significant(P<0.05). Conclusion Endoscopic tissue glue under endoscopy alone and endoscopic lauryl alcohol combined with tissue glue have significant curative effects in the treatment of EGVB patients, both of which have a high success rate of hemostasis and can control the recent rebleeding rate, however, the use of lauryl alcohol combined with tissue glue under endoscopy can more effectively reduce the long-term rebleeding rate in patients with EGVB, and has fewer complications, which can help improve the prognosis of patients, and is worthy of clinical application.

关 键 词：内镜 聚桂醇 组织胶 食管胃静脉曲张出血 近远期再出血 并发症 

分 类 号：R575.2[医药卫生—消化系统]