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作 者:赵瑞泉 罗金兵 王健 ZHAO Ruiquan;LUO Jinbing;WANG Jian(Health Services Center of Tuanjiehu Community of Chaoyang District of Beijing city,Beijing,100026,China)
机构地区:[1]北京市朝阳区团结湖社区卫生服务中心全科,北京100026
出 处:《当代医学》2022年第21期152-154,共3页Contemporary Medicine
摘 要:目的 探讨阿尔茨海默病与轻度认知功能障碍的相关因素及早期大规模筛查方法的优劣。方法 选取2019年6—10月团结湖社区年龄为65岁以上的老年人作为研究对象,具有6年及以上受教育经历,应用平板电脑以人机对话方式测评脑功能,认知快速测评、记忆快速测评功能异常后,再进行主诉认知、执行功能、反应速度、工作记忆、视空间能力、言语能力测评。结果 参与本研究评测者共311名,其中认知功能减退93名,患病率为29.90%;男性患病率为35.64%,女性为27.14%,不同性别患病率比较差异无统计学意义;65~74岁患病率为24.43%,75~84岁患病率为38.14%,不同年龄段患病率比较差异有统计学意义(P<0.05);单纯糖尿病患者患病率为41.38%,明显高于无慢性病者的24.05%(P<0.05)。结论 年龄是认知功能减退最主要的因素,糖尿病与认知功能障碍明显相关,不同性别患病率无显著差异,说明认知快速测评是适合阿尔兹海默尔病大规模筛查的方法。Objective To explore the related factors of Alzheimer’s disease and mild cognitive impairment and the advantages and disadvantages of early large-scale screening methods. Methods Select the elderly over 65 years old from June to October 2019 in Tuanjiehu community, with 6years or more education experience, and use tablet computer to conduct brain function evaluation by man-machine dialogue. After the cognitive rapid assessment and the memory rapid assessment function abnormality, the main complaints of cognition, executive function, reaction speed, working memory, visuospatial ability, and speech ability should be assessed. Results A total of 311 participants participated in the evaluation of this study, of which 93 were cognitively impaired, with the prevalence rate was 29.90%;the prevalence rate was 35.64% in males and 27.14% in females, and there was no significant difference in the prevalence rates between different genders;the prevalence rate of 65-74 years old was 24.43%, and the prevalence rate of 75-84 years old was 38.14%. There was statistically significant difference in the prevalence rate among different age groups(P<0.05).The prevalence rate of diabetic patients was 41.38%, which was singnificantly higher than 24.05% of no diabetics(P<0.05). Conclusion Age is the dominant factor of cognitive decline, diabetic is positive relative factor of cognitive decline, and there is no conspicuous difference of prevalence between men and women, and rapid cognitive assessment is a propriety way to widely screen of Alzheimer’ s disease.
分 类 号:R161.7[医药卫生—公共卫生与预防医学]
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