运动干预对青少年轻、中度特发性脊柱侧弯患者疗效的Meta分析  

Efficacy of exercise intervention in adolescents with mild to moderate idiopathic scoliosis:a meta-analysis

作　　者：张威[1,2] 卜淑敏 王涛[1,3] 汪普奎 ZHANG Wei;BO Shumin;WANG Tao;WANG Pukui(Capital University of Physical Education and Sports,Beijing 100191,P.R.China;College of Basic Medicin,Jining Medical University,Jining 272067,P.R.China;Schol of Physical Education,Liaocheng University,Liaocheng 252059,P.R.China)

机构地区：[1]首都体育学院,北京100191 [2]济宁医学院基础医学院,山东济宁272067 [3]聊城大学体育学院,山东聊城252059

出　　处：《中国循证医学杂志》2022年第8期896-900,共5页Chinese Journal of Evidence-based Medicine

摘　　要：目的系统评价运动干预对青少年轻、中度特发性脊柱侧弯(AIS)患者的疗效。方法计算机检索PubMed、Web of Science、The Cochrane Library、WanFang Data和CNKI数据库,搜集运动干预对青少年轻、中度AIS患者疗效的随机对照试验(RCT),检索时限均从建库至2021年11月。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用Stata 16.0软件进行Meta分析。结果共纳入11个RCT,包括638例患者。Meta分析结果显示:运动干预可显著改善AIS患者脊柱Cobb角[MD=-1.65,95%CI(-2.63,-0.68),P<0.01],降低躯干旋转角(ATR)[MD=-0.68,95%CI(-0.96,-0.40),P<0.01],提高肺活量(FVC)[MD=0.63,95%CI(0.10,1.15)P=0.02],但两组在第一秒用力呼气容积(FEV_(1))和FEV_(1)/FVC的差异无统计学意义。结论当前证据显示运动干预能改善AIS患者脊柱Cobb角、降低ATR、提高FVC。受纳入研究数量和质量的限制,上述结论尚待更多高质量研究予以验证。Objective To systematically review the efficacy of exercise intervention in adolescents with mild to moderate idiopathic scoliosis(AIS).Methods PubMed,Web of Science,The Cochrane Library,WanFang Data and CNKI databases were electronically searched to collect randomized controlled trials(RCTs)on the efficacy of exercise intervention in adolescents with mild to moderate AIS from inception to November 2021.Two reviewers independently screened the literature,extracted data and assessed the risk of bias of the included studies.Meta-analysis was then performed using Stata 16.0 software.Results A total of 11 RCTs involving 638 patients were included.The results of meta-analysis showed that exercise intervention significantly improved the Cobb angle of the spine in patients with AIS(MD=-1.65,95%CI-2.63 to-0.68,P<0.01),reduced the angle of trunk rotation(ATR)(MD=-0.68,95%CI-0.96 to-0.40,P<0.01),and increased their forced vital capacity(FVC)(MD=0.63,95%CI 0.10 to 1.15,P=0.02).However,there was no statistically significant improvement in the forced expiratory volume in the first second(FEV_(1))or the ratio of FEV_(1)/FVC between the two groups.Conclusion Current evidence shows that the exercise intervention could improve the Cobb angle of the spine,reduce ATR and enhance FVC.Due to the limited quality and quantity of the included studies,more high-quality studies are needed to verify the above conclusion.

关 键 词：运动干预 青少年 特发性脊柱侧弯 系统评价 META分析 随机对照试验 

分 类 号：R682.13[医药卫生—骨科学]