义齿软衬材料抗菌改性的研究进展  

Progress of research on antibacterial modification of denture soft lining material

作　　者：朱炳震 李碧榕 苏屹坤 伍韩雪 王景云[1] ZHU Bingzhen;LI Birong;SU Yikun;WU Hanxue;WANG Jingyun(Department of VIP,Stomatology Hospital,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学口腔医院VIP综合科,吉林长春130021

出　　处：《口腔医学》2022年第8期759-763,共5页Stomatology

摘　　要：义齿软衬材料是一种树脂基或硅基弹性衬垫,可以帮助均匀分配咬合载荷,减轻局部过大应力,提高患者舒适度,常用于活动义齿修复。然而,软衬材料自身表面结构和性能易导致微生物的黏附定植,尤其是白念珠菌,进而引发义齿性口炎。因此,软衬材料的抗菌改性可以大大提高其临床使用价值。目前主要措施有添加抗菌填料(如传统抗菌药物、天然提取物、无机金属抗菌剂),光动力抗菌化疗,低温等离子体表面处理等。该文概述了目前义齿软衬材料抗菌改性的主要措施和研究进展,探讨了其抗菌机制和对材料理化性能的影响。Denture soft lining material is a kind of resin-based or silicon-based elastic liner,which can help the uniform distribution of occlusal load,reduce local excessive stress and improve patients′ comfort level.It is often used in removable denture restoration.However,the surface structure and properties of soft lining materials can easily lead to microbial adhesion and colonization,especially Candida albicans,which can lead to denture stomatitis.Therefore,the antibacterial modification of soft lining material can greatly improve its clinical application value.At present,main measures include adding antibacterial fillers,such as traditional antimicrobial agents,natural extracts,inorganic metal antimicrobial agents,photodynamic antimicrobial chemotherapy,protective non-thermal plasma treatments and so on.In this paper,main measures and progress of research on antibacterial modification of denture soft lining materials were summarized,and its antibacterial mechanism and effect on the physical and chemical properties of materials were discussed.

关 键 词：软衬材料 义齿性口炎 抗菌性能 

分 类 号：R783.1[医药卫生—口腔医学]