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作 者:徐金杰 郭洪雷[1] 胡良皞[1] XU Jinjie;GUO Honglei;HU Lianghao(Department of Gastroenterology,Changhai Hospital,Shanghai 200433,China)
出 处:《临床肝胆病杂志》2022年第8期1941-1944,共4页Journal of Clinical Hepatology
基 金:国家自然科学基金(82070664,81770635);上海市科技创新行动计划技术标准项目(19DZ2201900);上海市曙光计划(20SG36)。
摘 要:远端胆管良性狭窄是由医源性损伤、慢性炎症、胆管结石等非肿瘤性因素所引起,受累胆管长期受到刺激导致纤维组织增生、胆管腔狭窄,进而出现反复发作的胆管炎、梗阻性黄疸和肝功能受损。缓解远端胆管梗阻并保持胆道长期通畅是远端胆管良性狭窄的治疗核心。随着内窥镜下逆行胰胆管技术的不断革新,内镜下狭窄扩张术、支架植入术以及磁压吻合术等新技术逐渐成为远端胆管良性狭窄的有效治疗手段。本文就远端胆管良性狭窄的内镜治疗进展进行阐述,以期为临床研究提供参考。Benign distal biliary strictures(BDBS)are fibrous tissue proliferation and biliary stricture caused by long-term stimulation of the affected bile ducts due to non-neoplastic factors such as iatrogenic injury,chronic inflammation,and bile duct stones,which further leads to recurrent cholangitis,obstructive jaundice,and liver impairment.Relieving distal biliary obstruction and maintaining bile duct patency for a long time are the core of the treatment of BDBS.With the continuous innovation of endoscopic retrograde cholangiopancreatography techniques,new techniques such as endoscopic stenosis dilatation,stent implantation,and magnetic compression anastomosis are gradually becoming effective treatment methods for BDBS.This article elaborates on the advances in endoscopic therapy for BDBS,so as to provide a reference for clinical research.
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