A novel analysis of Scheimpflug total corneal refractive power following corneal cross-linking in mild to moderate keratoconus  

作　　者：Chao Pan Wei-Na Tan Dan Chen Yu Liu Hao-Yu Wang Deng-Feng Liang Yan-Jun Hua Xiao-Hua Lei Qing-Yan Zeng Shao-Zhen Zhao 

机构地区：[1]Tianjin Key Laboratory of Retinal Functions and Diseases,Tianjin Branch of National Clinical Research Center for Ocular Disease,Eye Institute and School of Optometry,Tianjin Medical University Eye Hospital,Tianjin,China [2]Hankou Aier Eye Hospital,Wuhan,Hubei Province,China [3]School of Ophthalmology,Central South University,Changsha,Hunan Province,China [4]Department of Ophthalmology,Shanghai Jiao Tong University Affiliated Sixth People’s Hospital,Shanghai,China

出　　处：《International Journal of Ophthalmology(English edition)》2022年第5期728-735,共8页国际眼科杂志（英文版）

基　　金：National Natural Science Foundation of China(No.81970769);Hunan Province Technology Innovation Guidance Program(No.2018SK50108);Wuhan City Medicine Research Project(No.WX19C12);Ophthalmology and Otorhinolaryngology College of Hubei University of Science and Technology Research Development Fund Project(No.2020XZ38)。

摘　　要：AIM:To detect an earlier improvement in mild to moderate keratoconus following corneal cross-linking(CXL)with total corneal refractive power(TCRP)using ray tracing method.METHODS:A total of 40 eyes of 30 consecutive patients who underwent CXL for progressive keratoconus were retrospectively enrolled.The following keratometric parameters provided by Pentacam HR,including maximum keratometry(Kmax),steepest keratometry(Ksteep),3 mm zonal TCRP centered over corneal apex(TCRPapex,zone 3 mm),zonal mean keratometry and TCRP centered over corneal cone(Kmcone,zone and TCRPcone,zone 1,2,3 mm)were evaluated preoperatively and 1,3,6,and 12 mo postoperatively.Groups 1 and 2 were defined based on Kmax at postoperative 1 mo as improved(the initial improvement group)or worsen(the initial deterioration group)compared to the preoperative level.RESULTS:In the overall group,only keratometric parameters based on ray tracing method displayed significant improvement early at 3 mo postoperatively,in which TCRPcone,zone 1 mm and 2 mm exhibited the largest flattening(0.57 D and 0.53 D,respectively).In Group 1,only Kmax,Kmcone,zone 2 mm and TCRPcone,zone 2 mm showed significant improvement initially at 1 mo postoperatively,in which Kmax exhibited the largest improvement(1.05 D),followed by TCRPcone,zone 2 mm(0.82 D).In Group 2,only keratometric parameters based on ray tracing method and Kmcone,zone 3 mm showed slight but not significant improvement early at 3 mo,in which TCRPcone,zone 3 mm displayed the most improvement(0.19 D),followed by TCRPcone,zone 2 mm(0.15 D).CONCLUSION:The findings indicate that a 2 mm zonal TCRP centered over Kmax could earlier detect keratometric improvement by CXL compared to other commonly used parameters in mild to moderate keratoconic eyes.

关 键 词：KERATOCONUS corneal cross-linking KERATOMETRY total corneal refractive power ray tracing 

分 类 号：R779.6[医药卫生—眼科]