消化性溃疡患者上消化道出血发生状况及其影响因素  

Occurrence and Influencing Factors of Upper Gastrointestinal Bleeding in Patients with Peptic Ulcer

作　　者：邢燕 刘小玲[1] XING Yan;LIU Xiao-ling(Department of Gastroenterology,Henan Hongli Hospital,Xinxiang,Henan,453400,China)

机构地区：[1]河南宏力医院消化内科,河南新乡453400

出　　处：《黑龙江医学》2022年第15期1805-1807,共3页Heilongjiang Medical Journal

摘　　要：目的:探讨消化性溃疡患者上消化道出血发生状况及其影响因素。方法:选取2019年1—12月河南宏力医院接受治疗的85例消化性溃疡患者作为研究对象,观察所有入选者上消化道出血发生状况,并收集患者一般资料,分析可能影响消化性溃疡患者上消化道出血的相关因素。结果:85例消化性溃疡患者发生上消化道出血19例,占22.35%。未发生上消化道出血66例,占77.65%。经单因素分析显示,消化性溃疡患者发生上消化道出血与性别、年龄、体重指数、婚姻状况、吸烟史无关,差异无统计学意义(χ^(2)=0.368、1.762、1.529,P>0.05;t=1.124、1.739,P>0.05),消化性溃疡患者发生上消化道出血可能与病程、心理状况、饮食习惯、非甾体类抗炎药用药史、幽门螺杆菌(Hp)感染史有关,差异有统计学意义(t=10.962,P<0.05;χ^(2)=7.499、5.006、16.587、13.935,P<0.05)。经logistic回归分析显示,病程较长、心理状况不佳、不良饮食习惯、有非甾体类抗炎药用药史、有Hp感染史是消化性溃疡患者发生上消化道出血的影响因素,差异有统计学意义(OR>1,P<0.05)。结论:消化性溃疡患者发生上消化道出血风险较高,病程较长、不良饮食习惯、有非甾体类抗炎药用药史、有Hp感染史是患者发生上消化道出血的影响因素,临床可通过改善患者饮食习惯、给予心理疏导、调整用药、根除Hp等综合干预方案,以降低上消化道出血发生率。Objective:To investigate the occurrence and influencing factors of upper gastrointestinal bleeding in patients with peptic ulcer.Methods:A total of 85 patients with peptic ulcer who were treated in the hospital from January 2019 to December 2019 were selected as the research objects.The occurrence of upper gastrointestinal hemorrhage in all selected patients was ob⁃served,and the general information of the patients was collected.Factors that may affect upper gastrointestinal bleeding in peptic ulcer patients were analyzed.Results:Among the 85 patients with peptic ulcer,19 had upper gastrointestinal bleeding,accounting for 22.35%,and 66 did not have upper gastrointestinal bleeding,accounting for 77.65%.Univariate analysis showed that the occur⁃rence of upper gastrointestinal bleeding in patients with peptic ulcer was not associated with gender,age,body mass index,marital status,and smoking history,and the difference was not statistically significant(χ^(2)=0.368,1.762,1.529,t=1.124,1.739,P>0.05).The occurrence of upper gastrointestinal bleeding in patients with peptic ulcer may be related to the course of disease,psychologi⁃cal status,dietary habits,history of non-steroidal anti-inflammatory drug use,history of Helicobacter pylori(Hp)infection,and the difference was statistically significant(t=10.962,χ^(2)=7.499,5.006,16.587,13.935,P<0.05).Logistic regression analysis showed that longer course of disease,poor psychological status,poor eating habits,a history of non-steroidal anti-inflammatory drugs,and a history of Hp infection were the influencing factors of upper gastrointestinal bleeding in patients with peptic ulcer,and the difference was statistically significant(OR>1,P<0.05).Conclusion:Patients with peptic ulcer have a higher risk of upper gastrointestinal bleeding.Longer course of disease,poor dietary habits,a history of non-steroidal anti-inflammatory drug use,and a history of H.pylori infection are the influencing factors of upper gastrointestinal bleeding in patients.Clinically,comprehensive inter

关 键 词：消化性溃疡 上消化道出血 饮食习惯 非甾体类抗炎药 幽门螺杆菌 

分 类 号：R573.1[医药卫生—消化系统]