特发性非肝硬化门脉高压症的肝脏病理及影像特征  

Pathological and imaging features of idiopathic non-cirrhotic portal hypertension

作　　者：谭明洁 刘晖[2] 丁惠国 Ming-Jie Tan;Hui Liu;Hui-Guo Ding(Department of Gastrointestinal and Hepatology,Beijing You’An Hospital,Capital Medical University,Beijing 100069,China;Department of Pathology,Beijing You’An Hospital,Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京佑安医院肝病消化中心,北京市100069 [2]首都医科大学附属北京佑安医院病理科,北京市100069

出　　处：《世界华人消化杂志》2022年第16期729-734,共6页World Chinese Journal of Digestology

基　　金：国家自然科学基金,No.81970525。

摘　　要：特发性非肝硬化门脉高压症(idiopathic non-cirrhotic portalhypertension,INCPH)是一种病因不明的肝门窦血管性疾病.临床以门脉高压的症状和体征,而无肝硬化为特征,初次误诊漏诊率极高.肝活检为明确诊断的唯一途径.近年来,CT影像等非侵入性诊断INCPH成为关注的热点.本文归纳了INCPH的病理、CT/MRI特征以及与肝硬化的鉴别要点,旨在提高临床医生对INCPH的认识,减少初次诊断的误诊漏诊率.Idiopathic non-cirrhotic portal hypertension(INCPH),a kind of portal sinus vascular disease with unknown etiology,is characterized by the presence of clinical signs and symptoms of portal hypertension(PH) in the absence of liver cirrhosis or known risk factors accountable for PH.It has an extremely high rate of initial misdiagnosis and underdiagnosis.Liver biopsy is the only way to make a definitive diagnosis.Non-invasive modalities,such as CT imaging,are becoming a hot topic of interest in recent years.This article summarizes the pathological and CT/MRI features of INCPH and the key points of differentiation from cirrhosis,to improve clinicians’ understanding of INCPH and reduce the rate of initial misdiagnosis and missed diagnoses.

关 键 词：门静脉高压 非肝硬化 病理学 电子计算机X射线断层扫描 核磁共振成像 

分 类 号：R575.2[医药卫生—消化系统]