The grey matter volume and fractional amplitude of low-frequency fluctuation alterations in cerebral small vessel disease patients with subcortical ischemic depression and their relationship with brain derived neurotrophic factor gene polymorphism  

作　　者：ZHOU Xia 周霞(Dept Neurol,1st Affil Hosp,Anhui Med Univ,Hefei 230022)

机构地区：[1]Dept Neurol,1st Affil Hosp,Anhui Med Univ,Hefei 230022

出　　处：《China Medical Abstracts(Internal Medicine)》2022年第2期123-124,共2页中国医学文摘（内科学分册（英文版）

摘　　要：Objective To investigate the relationship between brain derived neurotrophic factor (BDNF) gene polymorphism and the change of grey matter volume (GMV) and fractional amplitude of low-frequency fluctuation(fALFF) in cerebral small vessel disease (CSVD) patients with subcortical ischemic depression (SID).Methods Eighty-seven CSVD patients in the First Affiliated Hospital of Anhui Medical University were enrolled from July 2017 to November 2020 and divided into CSVD-SID group [Geriatric Depression Scale (GDS) score> 10] and CSVD-non-depression group (CSVD-ND group, GDS score≤10) according to GDS.

关 键 词：PATIENTS alterations cerebral 

分 类 号：R743[医药卫生—神经病学与精神病学] R749.4[医药卫生—临床医学]