Noncirrhotic portal hypertension due to peripheral T-cell lymphoma,not otherwise specified:A case report  

作　　者：Miao-Miao Wu Wen-Jun Fu Jia Wu Lin-Lin Zhu Ting Niu Rong Yang Jin Yao Qiang Lu Xiao-Yang Liao 

机构地区：[1]General Practice Ward/International Medical Center Ward,General Practice Medical Center,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China [2]Department of Haematology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China [3]Department of Radiology,West China Hospital of Sichuan University,Chengdu 610041,Sichuan Province,China [4]Department of Ultrasound,West China Hospital of Sichuan University,Chengdu 610041,Sichuan Province,China

出　　处：《World Journal of Clinical Cases》2022年第26期9417-9427,共11页世界临床病例杂志

摘　　要：BACKGROUND Peripheral T-cell lymphoma(PTCL),an aggressive and rare disease that belongs to a heterogeneous group of mature T-cell lymphomas,develops rapidly and has a poor prognosis.Early detection and treatment are essential to improve patient cure and survival rates.Here,we report a rare case of PTCL with clinical presentation of noncirrhotic portal hypertension,which provides a basis for early vigilance of lymphomas in the future.CASE SUMMARY A 65-year-old Chinese woman was admitted to our hospital because of abdominal distension for 3 months and pitting oedema of both lower limbs for 2 months.Physical examinations and associated auxiliary examinations showed the presence of hepatosplenomegaly,and her hepatic venous pressure gradient was 10 mmHg.Immunohistochemical analysis of the liver biopsy confirmed the diagnosis of PTCL.The patient underwent combination therapy with dexamethasone,VP-16,and chidamide.Unfortunately,after 41 days of chemotherapy,the patient died of multiple organ failure.CONCLUSION PCTL accompanied by noncirrhotic portal hypertension is rarely reported.This case report discusses the diagnosis of a patient according to the literature.

关 键 词：Noncirrhotic portal hypertension ASCITES Peripheral T-cell lymphoma LYMPHOMA CHIDAMIDE Case report 

分 类 号：R733[医药卫生—肿瘤]