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作 者:张喜良 ZHANG Xi-liang(Department of Medical Affairs,Donggang Central Hospital,Dandong 118300,China)
机构地区:[1]辽宁省丹东东港市中心医院医务科,118300
出 处:《中国现代药物应用》2022年第15期127-129,共3页Chinese Journal of Modern Drug Application
摘 要:目的分析^(89)Sr联合局部放疗治疗多发性骨转移癌(BM)的临床疗效。方法64例多发性BM患者,依据治疗方式不同分为对照组和研究组,每组32例。对照组患者给予局部放疗,研究组患者在对照组基础上联合应用^(89)Sr治疗。比较两组患者骨病灶有效性、疼痛有效性。结果研究组患者病灶总有效率为100.0%,高于对照组的68.8%,差异具有统计学意义(P<0.05)。研究组患者疼痛总有效率为100.0%,高于对照组的62.5%,差异具有统计学意义(P<0.05)。结论给予多发性BM患者联合使用局部放射及^(89)Sr进行治疗,可更为显著地缓解BM患者的疼痛,提高骨病灶的治疗有效性。Objective To analyze the clinical efficacy of^(89)Sr combined with local radiotherapy in the treatment of multiple bone metastases(BM).Methods A total of 64 patients with multiple BM were divided into control group and research group according to different treatment methods,with 32 cases in each group.Patients in the control group were treated with local radiotherapy,and patients in the research group were treated with^(89)Sr on the basis of the control group.The effectiveness of bone lesions and the effectiveness of pain were compared between the two groups.Results The total effective rate of lesions in the research group was 100.0%,which was higher than 68.8%in the control group,and the difference was statistically significant(P<0.05).The total effective rate of pain in the research group was 100.0%,which was higher than 62.5%in the control group,and the difference was statistically significant(P<0.05).Conclusion The combined use of local radiation and^(89)Sr in the treatment of multiple BM patients can more significantly relieve the pain of BM patients and improve the therapeutic efficacy of bone lesions.
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