幽门螺杆菌与胃肠及胃肠外疾病关系的研究进展  

Advances in the relationship between Helicobacter pylori and gastrointestinal and extra-gastrointestinal diseases

作　　者：黄翠香 陈曦(综述) 包郁[1] 李强(审校)[3] HUANG Cuixiang;CHEN Xi;BAO Yu;LI Qiang(Department of Endoscopy Center,Sichuan Cancer Hospital,Chengdu,Sichuan 610041,China;Department of Gastroenterology,Affiliated Hospital of Southwest Medical University,Luzhou,Sichuan 646000,China;Department of Thoracic Surgery,Sichuan Cancer Hospital,Chengdu,Sichuan 610041,China)

机构地区：[1]四川省肿瘤医院内镜诊治部,成都610041 [2]西南医科大学附属医院消化内科,四川泸州646000 [3]四川省肿瘤医院胸外科,成都610041

出　　处：《重庆医学》2022年第17期3029-3033,共5页Chongqing medicine

基　　金：国家重点研发计划项目(2020YFB0408400);四川省科技厅重点研发项目(2019YFG0517)。

摘　　要：幽门螺杆菌(Hp)在全世界约50%的人口中存在,在发展中国家感染率达70%以上,已经证实慢性胃炎、胃十二指肠溃疡、胃癌、胃黏膜相关淋巴组织(MALT)淋巴瘤等疾病与Hp感染有关,Hp感染引起的胃肠外疾病目前也是一个研究热点,其机制可能涉及炎性反应、自身免疫等多方面。该文就Hp感染与部分胃肠疾病、胃肠外疾病的关系及其可能的机制进行综述,以期为临床诊治及早期预防提供参考。Helicobacter pylori(Hp)exists in about 50%of the world’s population,and the infection rate in developing countries reaches more than 70%.It has been confirmed that chronic gastritis,gastroduodenal ulcer,gastric cancer,gastric mucosa-associated lymphoid tissue(MALT)lymphoma and other diseases are related to Hp infection.Extra-gastrointestinal diseases caused by Hp infection are also a research hotspot at present,and the mechanism may involve inflammation,autoimmunity,and other aspects.This article summarizes the relationship between Hp infection and some gastrointestinal diseases,extra-gastrointestinal diseases,and its possible mechanisms,and provides references for clinical diagnosis and treatment and early prevention.

关 键 词：幽门螺杆菌 胃肠疾病 胃肠外疾病 相关性 发病机制 综述 

分 类 号：R573[医药卫生—消化系统]