咽旁间隙肿瘤切除术后并发霍纳综合征1例  

Horner syndrome after surgical treatment of parapharyngeal space mass:A case report

作　　者：辛旺 项奕[1,2] 李程 张立 XIN Wang;XIANG Yi;LI Cheng;ZHANG Li(Department of Ophthalmology,The Central Hospital of Wuhan,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014;Key Laboratory for Molecular Diagnosis of Hubei Province,The Central Hospital of Wuhan,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014;Department of Ophthalmology,Postgraduate Training Base of Wuhan Central Hospital,Hubei University of Medicine,Shiyan Hubei 442000;Department of Otolaryngology,The Central Hospital of Wuhan,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430014,China)

机构地区：[1]华中科技大学同济医学院附属武汉中心医院眼科,武汉430014 [2]华中科技大学同济医学院附属武汉中心医院分子诊断湖北省重点实验室,武汉430014 [3]湖北医药学院武汉市中心医院研究生培养基地眼科,湖北十堰442000 [4]华中科技大学同济医学院附属武汉中心医院耳鼻喉科,武汉430014

出　　处：《眼科学报》2022年第8期685-690,共6页Eye Science

基　　金：武汉市卫生健康科研基金(WX19Q29);湖北省卫生健康科研基金(WJ2019H376);眼科学国家重点实验室开放课题基金(2020KF05)。

摘　　要：霍纳综合征是一种由眼交感神经传出通路中任意部分中断所造成的临床综合征,常以上睑下垂、瞳孔缩小等眼部特征为主要临床表现,往往提示头、颈或胸部严重疾病或术后并发症的发生。现报告1例49岁的男性患者,曾在武汉市中心医院耳鼻喉科行右侧咽旁间隙肿物切除术,术后第1天出现右眼上睑下垂,瞳孔缩小,伴同侧面部无汗。术后随访半年,上述症状未见明显改善。右侧咽旁间隙肿物的病理结果证实为交感干神经鞘瘤,该病例临床较为罕见。Horner syndrome is caused by damage of the oculosympathetic pathway.It is a common disorder characterized by ocular signs such as ptosis and miosis,and these signs usually indicate the occurrence of severe head,neck and chest diseases or surgical complications.We report a case of 49-year-old male patient who underwent parapharyngeal space tumor resection in the Department of otolaryngology.On postoperative day one,the patient presented right eyelid drooping,the right pupil constricted,and the absence of sweating on the right side of the face.After six months of follow-up,the above signs still presented and showed no significant change.The pathological assessment of the resected parapharyngeal space tumor demonstrated that it is the sympathetic trunk schwannoma,which is relatively rare in clinical practice.

关 键 词：霍纳综合征 上睑下垂 瞳孔缩小 神经鞘瘤 眼交感神经通路 

分 类 号：R739.63[医药卫生—肿瘤] R771[医药卫生—临床医学]