食管癌术后并发急性呼吸衰竭危险因素分析  

Analysis of Concurrent Risk Factors for Acute Respiratory Failure After Oesophageal Cancer

作　　者：王海燕[1] 丁志丹[1] 秦爱敏[1] WANG Haiyan;DING Zhidan;QIN Aimin(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第一附属医院,450000

出　　处：《实用癌症杂志》2022年第9期1474-1476,1490,共4页The Practical Journal of Cancer

摘　　要：目的探讨食管癌术后并发急性呼吸衰竭(ARF)的危险因素。方法回顾性分析168例食管癌患者临床资料,分析食管癌术后并发ARF的相关影响因素。结果168例食管癌术后并发ARF 30例(17.86%);单因素分析显示:年龄、吸烟史、TNM分期、糖尿病、手术时间、术后肺部感染与食管癌术后并发ARF有关(P<0.05);性别、体重指数(BMI)、饮酒史、合并高血压、冠心病和手术方式、术中出血量、吻合部位、病变部位、分化程度、术后吻合口瘘与食管癌术后并发ARF无关(P>0.05);多因素分析显示:年龄≥70岁、吸烟史、TNM分期Ⅱ~Ⅲ期、糖尿病、手术时间>3 h、术后肺部感染是食管癌术后并发ARF的高危因素(P<0.05)。结论食管癌术后并发ARF与年龄、吸烟史、TNM分期、糖尿病、手术时间、术后肺部感染密切相关,针对各危险因素制定相应防治措施,可能减少ARF发生。Objective To investigate the risk factors of acute respiratory failure(ARF)after oesophageal cancer.Methods The clinical data of 168 patients with esophageal cancer were retrospectively analyzed,and the relevant influencing factors of postoperative ARF were analyzed.Results 168 cases of esophageal cancer were complicated with ARF 30(17.86%);Univariate analysis showed that age,smoking history,TNM stage,diabetes mellitus,surgery time,and postoperative pulmonary infection were associated with concurrent ARF after oesophageal cancer,The difference was statistical significant(P<0.05);Gender,body mass index(BMI),alcohol consumption history,combined hypertension,coronary heart disease and surgical mode,intraoperative bleeding,anastomosis site,lesion site,degree of differentiation,postoperative anastomotic fistula were not associated with postoperative ARF after esophageal cancer,The difference was not significantly significant(P>0.05);Multivariate analysis showed that age≥70 years,smoking history,TNM stage-stage,diabetes,surgical time>3 h,postoperative pulmonary infection are high risk factors for ARF after esophageal cancer(P<0.05).Conclusion ARF after esophageal cancer is closely related to age,smoking history,TNM stage,diabetes mellitus,operation time and postoperative lung infection.Corresponding prevention and treatment measures for various risk factors may reduce the occurrence of ARF.

关 键 词：急性呼吸衰竭 食管癌 危险因素 TNM分期 肺部感染 

分 类 号：R735.1[医药卫生—肿瘤]