脑型Wilson病儿童的情绪行为与社会生活能力特点研究  

Characteristics of emotional behaviour and social life ability in children with cerebral Wilson ' s disease

作　　者：金珊[1] 方向[1] 杨文明[1] 谢道俊[1] JIN Shan;FANG Xiang;YANG Wen-ming;XIE Dao-jun(Encephalopathy Center,the First Affiliated Hospital of Anhui University of Chinese Medicine,Hefei,Anhui 230031,China)

机构地区：[1]安徽中医药大学第一附属医院脑病中心,安徽合肥230031

出　　处：《中华全科医学》2022年第9期1455-1457,1501,共4页Chinese Journal of General Practice

基　　金：国家自然科学基金面上项目(81973825);安徽省2019年度高校自然科学研究项目(KJ2019A0457);安徽省2020年度自然科学基金面上项目(2008085MH264)。

摘　　要：目的 明确脑型Wilson病(WD)儿童的情绪行为和社会生活能力特点,及时发现隐匿性神经心理损害,采取更有针对性的个体化干预方案,纠正患儿异常情绪行为,提高社会生活能力。方法 选取于2019年1月—2020年12月在安徽中医药大学第一附属医院脑病中心住院治疗的30例脑型WD儿童为观察组,同期30例健康适龄儿童为对照组。应用Achenbach儿童行为量表及婴儿-初中生社会生活能力量表评定30例WD儿童和30例正常儿童情绪行为与社会生活能力特点,分析WD儿童情绪行为及社会生活能力与正常儿童之间的差异。结果情绪行为特点评定中,脑型Wilson病组攻击性、交往不良、社交退缩、违纪评分为8.0(7.0,9.0)分、4.0(3.0,5.0)分、3.0(3.0,4.0)分、4.0(3.0,5.0)分,对照组分别为6.0(4.0,7.0)分、3.0(1.8,3.0)分、1.0(1.0,2.0)分、1.0(1.0,2.0)分,2组比较差异有统计学意义(均P<0.05)。社会能力评定中,2组儿童作业操作评分比较差异无统计学意义(P>0.05);独立生活、运动、交往、集体活动、自我管理5个分项评分比较差异有统计学意义(均P<0.05)。结论 脑型Wilson病儿童存在显著的性格改变、易激惹、社交能力下降等情绪行为及生活能力异常,对于此类患者的治疗除重视临床症状的改善,还应重视精神心理的康复,使其具备更加完整的精神、心理功能和良好的社会适应能力。Objective To clarify the characteristics of emotional behaviour and social life ability of children with cerebral Wilson's disease(WD),to find concealed neuropsychological damage in time,to adopt more targeted individualised intervention programs and correct abnormal emotional behaviour,and to improve the social life ability of children.Methods Thirty children with cerebral WD in the Encephalopathy Center of the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine from January 2019 to December 2020 served as the observation group.Thirty healthy school-age children served as the control group in the same period.The characteristics of emotional behaviour and social life ability of 30 WD children and 30 normal children were assessed by Achenbach children's behaviour scale and infant junior middle school students'social life ability scale.The differences between WD children and normal children were analysed.Results The scores of aggression,poor communication,social withdrawal,and violation of discipline in the cerebral WD group were 8.0(7.0,9.0)points,4.0(3.0,5.0)points,3.0(3.0,4.0)points,4.0(3.0,5.0)points and the control group were 6.0(4.0,7.0)points,3.0(1.8,3.0)points,1.0(1.0,2.0)points,1.0(1.0,2.0)points,respectively.A significant difference existed between the two groups(all P<0.05).In the assessment of social ability,no significant difference existed between the two groups(P>0.05).A significant difference existed in the scores of independent life,sports,communication,collective activities,and self-management(all P<0.05).Conclusion Significant personality changes,irritability,decreased social ability and other emotional behaviour,and living ability abnormalities exist in children with cerebral WD.In addition to the improvement in clinical symptoms,the treatment of such patients should also pay attention to mental and psychological rehabilitation so that they can have more complete spiritual and psychological functions and good social adaptability.

关 键 词：WILSON病 情绪行为 生活能力 ACHENBACH儿童行为量表 婴儿-初中生社会生活能力量表 

分 类 号：R742.4[医药卫生—神经病学与精神病学] R179[医药卫生—临床医学]