Genomic Characterization of a Streptococcus suis Serotype 2 Isolated from a Human Patient  

作　　者：GUO Geng Lin GAO Hua Sheng WANG Zhuo Hao TAN Zhong Ming HAN Ming Xiao CHEN Qi DU Hong ZHANG Wei ZHANG Hai Fang 

机构地区：[1]College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,Jiangsu,China [2]Key Lab of Animal Bacteriology,Ministry of Agriculture,Nanjing 210095,Jiangsu,China [3]OIE Reference Lab'for Swine Streptococcosis,Nanjing 210095,Jiangsu,China [4]Department of Clinical Laboratory,The Second Affliated Hospital of Soochow University,Suzhou 215004,Jiangsu,China [5]NHC Key Laboratory of Enteric Pathogenic Microbiology,Jjiangsu Provincial Center for Disease Control and Prevention,Nanjng 210009,Jiangsu,China

出　　处：《Biomedical and Environmental Sciences》2022年第8期760-763,共4页生物医学与环境科学（英文版）

基　　金：supported by the National Natural Science Foundation of China [82172332];Gusu health youth talent of Suzhou [GSWS2019039,GSWS2020030];the Science and Technology Program of Suzhou [SKY2021007];Discipline Construction of The Second Affiliated Hospital of Soochow University [XKTJ-TD202001];Postgraduate Research&Practice Innovation Program of Jiangsu Province

摘　　要：Streptococcus suis(S. suis) is a Gram-positive zoonotic pathogen. S. suis infection in humans commonly causes meningitis, septicemia, arthritis,and streptococcal toxic shock-like syndrome(STSLS). S. suis has 29 serotypes, of which S. suis serotype 2(SS2) has the highest clinical isolation rate and strongest pathogenicity and causes most S. suis human infections.About 1,000 different sequence types(STs)were identified in S.suis based on multilocus sequence typing(MLST).Among these,STs,ST1,and ST7 belong to serotype 2 and are the major hazards of S.suis.in 1998 and 2005,two cases of SS2 human infection outbreak were reported in Jiangsu and Sichuan,China,causing 14 deaths and 38 deaths,respectively.

关 键 词：SUIS STREPTOCOCCUS HUMAN 

分 类 号：R378[医药卫生—病原生物学]