超重和肥胖与缺血性卒中的关系  

Association of overweight and obesity withischemic stroke

作　　者：刘悦[1] 王锐[1] 岳辉[1] 付锦[1] Liu Yue;Wang Rui;Yue Hui;Fu Jin(The Second Affiliated Hospital of Harbin Medical University,Harbin150086,China)

机构地区：[1]哈尔滨医科大学附属第二医院,哈尔滨150086

出　　处：《中华老年医学杂志》2022年第9期1122-1125,共4页Chinese Journal of Geriatrics

基　　金：黑龙江省自然科学基金(JJ2020LH1880)

摘　　要：缺血性卒中是引起人类死亡和成人残疾的主要原因之一, 肥胖是缺血性卒中的独立危险因素之一, 预防肥胖可减少患者发生首次卒中的概率。然而, 对于已经发生缺血性卒中的患者, 较高的体质指数(BMI)可能与缺血性卒中患者的死亡率降低、卒中复发减少、功能预后改善相关, 这种现象称为肥胖悖论。肥胖悖论的现象让我们看到了肥胖对缺血性卒中可能具有有益的一面。因此, 本文将以肥胖与缺血性卒中一级预防和二级预防的关系, 特别是肥胖悖论进行综述。Ischemic stroke is one of the main causes of death and disability in adults,and obesity is one of the independent risk factors for ischemic stroke and prevention of obesity can reduce the probability of patients'first stroke.However,for patients who havealready hadan ischemic stroke,a higher body mass index(BMI)may be correlated with a lower mortality in patients with ischemic stroke,reduced recurrence of stroke,and improved functional prognosis,a phenomenon known as the obesity paradox.The obesity paradox suggests that obesity may be beneficial in ischemic stroke.Therefore,this paper reviews the relationship between primary and secondary prevention of obesity and ischemic stroke,with a focus on theobesity paradox.

关 键 词：缺血性卒中 肥胖 脂肪类 

分 类 号：R743.3[医药卫生—神经病学与精神病学]