3D-T1-SPACE增强序列在大脑中动脉粥样硬化血管评估中的价值  

Value of 3D-T1-SPACE Enhancement Sequence in the Evaluation of Middle Cerebral Artery Atherosclerosis

作　　者：张亚莹 肖慧 朱来敏[1] 陈月芹[1] 魏君臣[1] ZHANG Yaying;XIAO Hui;ZHU Laimin;CHEN Yueqin;WEI Junchen(Department of Medical Imaging,The Affiliate Hospital of Jining Medical University,Jining Shandong 270029,China;Department of Radiology,The 900th Hospital of Joint Logistics Support Force,Fuzhou Fujian 350025,China)

机构地区：[1]济宁医学院附属医院医学影像科,山东济宁272029 [2]联勤保障部队第九○○医院放射诊断科,福建福州350025

出　　处：《中国医疗设备》2022年第9期65-68,84,共5页China Medical Devices

基　　金：福建省自然科学基金(2020J011135)。

摘　　要：目的探讨3.0 T磁共振3D-T1-可变反转角快速自旋回波(Sampling Perfection with Application Optimized Contrasts Using Different Fip Angle Evolution,3D-T1-SPACE)增强序列评估大脑中动脉(Middle Cerebral Artery,MCA)粥样硬化患者受累血管的临床价值。方法分析46例单侧MCA粥样硬化性狭窄患者临床、影像资料,对比评估3D-T1-SPACE增强、三维时间飞跃法磁共振血管成像(Three Dimensional Time of Flight Magnetic Resonance Angiography,3D-TOF-MRA)在测量管腔狭窄及病变长度方面与数字减影血管造影(Digtial Subtraction Angiography,DSA)的一致性。结果相比DSA,3D-T1-SPACE增强在评估管腔狭窄方面的一致性优于3D-TOF-MRA(ICC=0.91、0.80),而两者在测量病变长度方面均高于DSA(P<0.001);DSA、3D-TOF-MRA显示管腔局部轻微凹陷可疑狭窄时,3D-T1-SPACE增强序列可有效检出管壁微小斑块。结论3D-T1-SPACE增强序列能有效评估MCA粥样硬化管腔狭窄、病变长度及斑块特征,可作为MCA粥样硬化患者常规无创诊断及随访评估手段。Objective To explore the clinical value of 3.0 T magnetic resonance 3D-T1-sampling perfection with application optimized contrasts using different fip angle evolution(3D-T1-SPACE)enhanced sequence in the evaluation of involved vessels in patients with middle cerebral artery(MCA)atherosclerosis.Methods The clinical and imaging data of 46 patients with unilateral MCA atherosclerotic stenosis were analyzed to explore the consistency of 3D-T1-SPACE enhancement,three dimensional time of flight magnetic resonance angiography(3D-TOF-MRA)and digital subtraction angiography(DSA)in measuring lumen stenosis rate and lesion length.Results Compared with DSA,the consistency of 3D-T1-SPACE enhancement was better than that of 3D-TOF-MRA(ICC=0.91,0.80)in the evaluation of lumen stenosis,but both of them were higher than DSA in measuring lesion length(P<0.001).When DSA and 3D-TOF-MRA showed that the lumen was slightly depressed and suspected to be narrow,3D-T1-SPACE enhanced sequence could effectively detect small plaques on the wall of the vessel.Conclusion 3D-T1-SPACE enhancement sequence can effectively evaluate the rate of atherosclerotic stenosis,lesion length and plaque feature of middle cerebral artery,and can be used as a routine non-invasive diagnosis and follow-up evaluation of patients with MCA atherosclerosis.

关 键 词：动脉粥样硬化 大脑中动脉 3D-T1-可变反转角快速自旋回波 磁共振成像 

分 类 号：R743[医药卫生—神经病学与精神病学]