Unusual global outbreak of monkeypox:what should we do?  

作　　者：Miaojin Zhu Jia Ji Danrong Shi Xiangyun Lu Baohong Wang Nanping Wu Jie Wu Hangping Yao Lanjuan Li 

机构地区：[1]State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,National Clinical Research Center for Infectious Diseases,Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,The First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310003,China [2]Jinan Microecological Biomedicine Shandong Laboratory,Jinan 250117,China

出　　处：《Frontiers of Medicine》2022年第4期507-517,共11页医学前沿（英文版）

基　　金：supported by the National Key Research&Development Program of China(No.2021YFC2301204);Zhejiang Provincial Key Research&Development Program of China(No.2021C03043);Research Project of Jinan Microecological Biomedicine Shandong Laboratory.

摘　　要：Recently,monkeypox has become a global concern amid the ongoing COVID-19 pandemic.Monkeypox is an acute rash zoonosis caused by the monkeypox virus,which was previously concentrated in Africa.The re-emergence of this pathogen seems unusual on account of outbreaks in multiple nonendemic countries and the incline to spread from person to person.We need to revisit this virus to prevent the epidemic from getting worse.In this review,we comprehensively summarize studies on monkeypox,including its epidemiology,biological characteristics,pathogenesis,and clinical characteristics,as well as therapeutics and vaccines,highlighting its unusual outbreak attributed to the transformation of transmission.We also analyze the present situation and put forward countermeasures from both clinical and scientific research to address it.

关 键 词：MONKEYPOX POXVIRUSES VACCINE infectious diseases 

分 类 号：R511[医药卫生—内科学] R183[医药卫生—临床医学]