腹腔镜结直肠癌根治术治疗结直肠癌的效果观察  

Effect Observation on Colorectal Cancer Treated with Laparoscopic Radical Surgery

作　　者：桑温昌[1] 杨林[1] 张英杰 肖琦[1] 莫龙腾 SANG Wen-chang;YANG Lin;ZHANG Ying-jie;XIAO Qi;MO Long-teng(No.1 Dept.of Surgery,Huaiyin People’s Hospital,Jinan,Shandong 250021)

机构地区：[1]济南市槐荫人民医院外一科,山东济南250021

出　　处：《中国肛肠病杂志》2022年第7期4-6,共3页Chinese Journal of Coloproctology

摘　　要：目的:探讨腹腔镜结直肠癌根治术治疗结直肠癌的效果。方法:将60例结直肠癌患者随机分为观察组和对照组,每组30例。观察组患者采用腹腔镜结直肠癌根治术治疗,对照组患者采用开腹结直肠癌根治术治疗,比较2组患者手术相关指标,手术前后氧化应激指标、免疫功能指标及能量代谢指标。结果:观察组患者术后首次排气时间、住院时间和尿管留置时间均短于对照组(P<0.05)。手术前2组患者各项指标比较差异无统计学意义(P>0.05);手术后观察组患者血清超氧化物歧化酶(SOD)水平高于对照组(P<0.05),血清丙二醛(MDA)低于对照组(P<0.05);观察组患者CD3+、CD4+水平均高于对照组(P<0.05),CD8+水平低于对照组(P<0.05);观察组患者血清前白蛋白(PA)、血清白蛋白(ALB)、转铁蛋白(TRE)、视黄醇结合蛋白(RBP)水平均高于对照组(P<0.05)。结论:腹腔镜结直肠癌根治术可明显缩短患者住院时间,有效减轻氧化应激反应,对患者机体免疫功能、能量代谢影响较小,有助于促进患者术后恢复。Objective To investigate the effect of laparoscopic radical surgery in the treatment of colorectal cancer.Methods Randomly divided 60colorectal cancer patients treated in author’s hospital into observation group(30cases,received laparoscopic radical surgery for their colorectal cancer)and control group(30cases,open radical surgery);then,compared both groups’relevant operative norms,oxidative stress norms before and after surgery,immunofunctional norms,and energy metabolism norms.Results After surgery,the time for first flatus from anus,for hospitalization,and for catheter-indwelling in observation group all were shorter than in control group(P<0.05);Before surgery,in above-mentioned classes of norms there was no statistical difference between the two groups(P>0.05),but after surgery,1)in observation group the levels of SOD,MDA was respectively higher,lower than in control group(all,P<0.05);2)in observation group the levels of CD3+and CD4+,as well as of CD8+were respectively higher,as well as lower than in control group(all,P<0.05);3)in observation group the levels of PA,ALB,TRE,and RBP were all higher than in control group(P<0.05).Conclusion Laparoscopic radical surgery for colorectal cancer can significantly shorten hospitalization time,effectively reduce oxidative stress response,and with less influence on body immunofunction and energy metabolism,which is helpful to patients’postoperative recovery.

关 键 词：结直肠癌 腹腔镜 根治术 

分 类 号：R735.34[医药卫生—肿瘤]