Liddle综合征合并Gordon综合征一例  

Liddle syndrome complicated with Gordon syndrome:A case report

作　　者：潘小蓉 方湘 李东泽[2] 杨荣 伍佳[1] 张亚琳[1] 姚易 高晨曦 廖晓阳[1] PAN Xiaorong;FANG Xiang;LI Dongze;YANG Rong;WU Jia;ZHANG Yalin;YAO Yi;GAO Chenxi;LIAO Xiaoyang(International Medical Center/Department of General Practice and National Clinical Research Center for Geriatrics,West China Hospital,Sichuan University,Chengdu,610041,P.R.China;Department of Emergency Medicine,West China Hospital,Sichuan University,Chengdu,610041,P.R.China)

机构地区：[1]四川大学华西医院特需医疗中心全科病房,国家老年疾病临床医学研究中心,成都610041 [2]四川大学华西医院急诊科,成都610041

出　　处：《中国胸心血管外科临床杂志》2022年第9期1236-1238,共3页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

基　　金：四川大学华西医院学科卓越发展1·3·5工程临床研究孵化项目(20HXFH050);国家老年疾病临床医学研究中心(四川大学华西医院)项目(Z20191009);四川省科学技术项目(20SYSX0293)。

摘　　要：Liddle综合征和Gordon综合征是两种罕见的单基因遗传性高血压病。Liddle综合征在年龄≤40岁的青年高血压患者中的患病率约1%。Gordon综合征目前在国内外的患病率尚不确定,常被误诊误治。二者的治疗均是针对基因突变位点的精准治疗,同时配合非药物治疗,均可达到满意的治疗效果。现报道1例Liddle综合征合并Gordon综合征案例及治疗,旨在与临床医生共同学习探讨,从而巩固和提高对本病的诊断及精准治疗。Liddle syndrome and Gordon syndrome are two rare single-gene inherited hypertension diseases. In patients≤40 years, the prevalence of Liddle syndrome is about 1% and Gordon syndrome is uncertain all over the word,for which is often misdiagnosed and mistreated. The therapies of those diseases are targeted at gene mutation sites, as well as combined with modified lifestyle, and can achieve satisfactory diseases control. This paper reports a patient who is diagnosed with Liddle syndrome and Gordon syndrome at the same time. We aimed to consolidate and improve the diagnosis and accurate treatment of those two diseases by sharing, studying and discussing together with clinical doctors.

关 键 词：LIDDLE综合征 Gordon综合征 青年 高血压 精准医学 病例报告 

分 类 号：R544.1[医药卫生—心血管疾病]