精准神经外科10年再出发:脑胶质瘤外科的信息化和体系化升级  

A decade of pecision neurosurgery:the informative and systematic upgrading of brain glioma surgery

作　　者：陈晓雷[1] 许百男[1] Chen Xiaolei;Xu Bainan(Department of Neurosurgery,the First Medical Center,Chinese People′s Liberation Army General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院第一医学中心神经外科医学部,北京100853

出　　处：《中华外科杂志》2022年第9期801-806,共6页Chinese Journal of Surgery

基　　金：国家重点研发计划(2018YFC1312602);国家自然科学基金(81771481)。

摘　　要：精准神经外科理念的发展及相关技术平台的建设对我国脑胶质瘤外科的发展有重要的推动作用。10年的发展历程中,通过医学和理工学科的多学科、多领域交叉融合,不断整合新的成像和导航手段,并积极进行临床转化研发与实践,使精准神经外科经历了从单纯解剖导航的“初创时代”,到基于多模态导航和术中MRI的“精准神经外科1.0”时代,再到信息化、体系化升级的“精准神经外科2.0”时代。我国学者通过不断努力和创新,取得了许多令人瞩目的成绩。未来,人工智能深度机器学习、多模态图像实时融合导航手术、光学成像、靶向分子影像等前沿技术将协同推动脑胶质瘤外科的发展,引领“精准神经外科3.0”时代的到来。Precision neurosurgery concept as well as the establishment of it′s technical platform,have played essential roles in promoting the modern surgical management of brain gliomas in China.In the past decade,the multidisciplinary integration of medical sciences and technology innovations has significantly promoted the clinical implementation of new imaging and novel navigation technology.With active clinical translational research and practice,precision neurosurgery has developed from“startup prologue”(simple anatomical navigation)to“precision neurosurgery 1.0”(intraoperative MRI with multimodal neuronavigation),followed by“precision neurosurgery 2.0”(informative and systematic upgrading).In the past decade,Chinese researchers have made significant and remarkable achievements in precision neurosurgery through continuous efforts and innovation.In the future,state-of-art technologies such as artificial intelligence on deep learning and machine learning,multimodal real-time navigation,intraoperative optical imaging,and targeted molecular imaging technology will promote the development of precision neurosurgery in a coordinated manner,leading to the advent of“precision neurosurgery 3.0”.

关 键 词：神经胶质瘤 神经外科 精准治疗 术中影像 多模态神经导航 

分 类 号：R739.41[医药卫生—肿瘤]