基于立体脑电图技术治疗难治性颞叶癫痫的研究进展  

Research progress in the treatment of refractory temporal lobe epilepsy based on stereotactic-electroencephalogram

作　　者：尹文杰 王小强[1] 李成龙 赵明睿 张新定[1] Yin Wenjie;Wang Xiaoqiang;Li Chenglong;Zhao Mingrui;Zhang Xinding(Department of Neurosurgery,Laboratory of Neurosurgery,Institute of Neurology,Lanzhou University,Lanzhou 730000,China)

机构地区：[1]兰州大学第二医院神经外科,神经外科实验室,兰州大学神经病学研究所,兰州730000

出　　处：《中华外科杂志》2022年第9期876-880,共5页Chinese Journal of Surgery

基　　金：兰州大学第二医院“萃英科技创新”临床拔尖技术研究(CY2020-BJ02)。

摘　　要：颞叶癫痫在所有局灶性癫痫中发病率最高,具有病因学、症状学及电生理特征多样,进展为难治性癫痫率高的特点。手术是治疗难治性颞叶癫痫的有效手段,但传统方法通常难以对致痫区进行准确定位,立体脑电图技术为致痫区的准确定位提供了有效手段。基于立体脑电图的射频热凝和MRI引导的激光间质热疗,为手术风险高、难度大的难治性癫痫患者的外科治疗提供了精准、微创的新选择。Temporal lobe epilepsy,with a variety of etiological,symptomatic,electrophysiological characteristics,has the highest incidence among all focal epilepsy,and a high rate of progression to refractory epilepsy.Surgery is an effective treatment,but traditional methods are usually difficult to accurately locate the epileptogenic zone,which may be resolved by stereotactic-electroencephalogram(SEEG)technique.Radiofrequency thermocoagulation and MRI-guided laser interstitial thermal therapy based on SEEG provide a new accurate and minimally invasive choice for refractory epilepsy patients with high surgical risk and difficulty.

关 键 词：癫痫 颞叶 电生理学 立体脑电图 射频热凝 激光间质热疗 

分 类 号：R742.1[医药卫生—神经病学与精神病学]